NBN Book of the Day - Jack Price, “The Future of Brain Repair: A Realist’s Guide to Stem Cell Therapy” (MIT Press, 2020)

A scientist assesses the potential of stem cell therapies for treating such brain disorders as stroke, Alzheimer’s disease, and Parkinson’s disease.

Stem cell therapies are the subject of enormous hype, endowed by the media with almost magical qualities and imagined by the public to bring about miracle cures. Stem cells have the potential to generate new cells of different types, and have been shown to do so in certain cases. Could stem cell transplants repair the damaged brain? In his book The Future of Brain Repair: A Realist's Guide to Stem Cell Therapy (MIT Press, 2020), neurobiologist Jack Price assesses the potential of stem cell therapies to treat such brain disorders as stroke, Alzheimer’s disease, Parkinson’s disease, and spinal cord injuries.

Certainly brain disorders are in need of effective treatments. These disorders don’t just kill, they disable, and conventional drug therapies have not had much success in treating them. Price explains that repairing the human brain is difficult, largely because of its structural, functional, and developmental complexity. He examines the self-repairing capacity of blood and gut cells—and the lack of such capacity in the brain; describes the limitations of early brain stem cell therapies for neurodegenerative disorders; and discusses current clinical trials that may lead to the first licensed stem cell therapies for stroke, Parkinson’s and macular degeneration. And he describes the real promise of pluripotential stem cells, which can make all the cell types that constitute the body.

New technologies, Price reports, challenge the very notion of cell transplantation, instead seeking to convince the brain itself to manufacture the new cells it needs. Could this be the true future of brain repair?

You can find more about Jack’s work here and here.

Galina Limorenko is a doctoral candidate in Neuroscience with a focus on biochemistry and molecular biology of neurodegenerative diseases at EPFL in Switzerland. To discuss and propose the book for an interview you can reach her at galina.limorenko@epfl.ch.

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The NewsWorthy - Trump Trial Highlights, Cause of Kobe Crash & ‘Wizard of Oz’ Remake- Wednesday, February 10th, 2021

The news to know for Wednesday, February 10th, 2021!

We'll tell you about:

  • chilling video that played at this week's impeachment trial and why one of Trump's lawyers says he was caught off-guard
  • what the World Health Organization says about that theory COVID-19 was leaked from a lab
  • what caused the crash that killed Kobe Bryant a year ago
  • the new name for a controversial syrup brand
  • when a new report says remote workers may need to return to the office 

Those stories and more in about 10 minutes! 

Head to www.theNewsWorthy.com to read more about any of the stories mentioned under the section titled 'Episodes' or see sources below...

This episode is brought to you by NativeDeo.com/newsworthy and MunkPack.com (Listen for the discount code)

Get ad-free episodes and support the show by becoming an INSIDER: www.theNewsWorthy.com/insider 

 

 

 

Sources:

Impeachment Trial Moves Forward: WaPo, AP, WSJ, Politico

Latest Relief Proposal: Reuters, CBS News, CNBC, The Hill

WHO Virus Origins Investigation: AP, BBC, WSJ, Reuters

CA COVID-19 Deaths: Reuters, NY Times, Johns Hopkins

MLB Spring Training Deal: WaPo, AP, MLB, Kinexon

NTSB Names Cause in Kobe Bryant Crash: USA Today, LA Times, AP, NTSB

Aunt Jemima Rebranded: AP, USA Today, NBC News, PepsiCo

‘Wizard of Oz’ Remake: AP, Variety, People

Alex Trebek’s Wardrobe Donated: Deadline, GMA, Variety, Jeopardy!, Jean Trebek

Work Wednesday: Workers’ Office Comeback: CNBC, The Conference Board, Pew Research

In the Bubble with Andy Slavitt - How to Lead During a Crisis (with Sully Sullenberger)

Dr. Bob talks about the importance of leadership, whether it's during a pandemic or a flight that's lost all engine power, with Captain Chesley "Sully" Sullenberger. The parallels between the two might not seem obvious, but Sully points out that the basic elements of good leadership can be applied in any situation. He also talks about how he and the crew landed Flight 1549 safely in the Hudson River, what lessons he took from that famous flight, and what caused him to speak out against what he calls a "vacuum of leadership" during the pandemic. Plus, what it's like to have Tom Hanks play you in a movie.

 

Follow Dr. Bob on Twitter @Bob_Wachter and check out In the Bubble’s new Twitter account @inthebubblepod.

 

Follow Sully Sullenberger on Twitter @Captsully. 

 

Keep up with Andy in D.C. on Twitter @ASlavitt and Instagram @andyslavitt.

 

In the Bubble is supported in part by listeners like you. Become a member, get exclusive bonus content, ask Andy questions, and get discounted merch at https://www.lemonadamedia.com/inthebubble/ 

 

Support the show by checking out our sponsors!

 

 

Check out these resources from today’s episode: 

 

 

To follow along with a transcript and/or take notes for friends and family, go to www.lemonadamedia.com/show/in-the-bubble shortly after the air date.

 

Stay up to date with us on Twitter, Facebook, and Instagram at @LemonadaMedia. For additional resources, information, and a transcript of the episode, visit lemonadamedia.com.

See omnystudio.com/listener for privacy information.

See omnystudio.com/listener for privacy information.

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Security Unlocked - Pluton: The New Bedrock for Device Security

Close your eyes, and imagine a world where booting up your computer wasn’t a susceptibility point for attacks. Imagine a Root of Trust that’s integrated into the CPU. Imagine all of your devices being protected against advanced attacks. Now, what if I told you there’s a cutting-edge processor that’s battle-tested for hardware penetrations, easy to update, and protects credentials, encryption keys, and personal data all at once? What if I told you it was already here, and your systems might already be using it?! Open your eyes, and get ready to be amazed! It’s Pluton, baby! Peter Waxman, Group Program Manager at Microsoft, joins hosts Nic Fillingham and Natalia Godyla in a tell-all about Pluton. Trust us, Pluton is sure to knock your SOCs off (that’s System on a Chip)!

Now that your eyes have been opened to a more secure system, we’d like to ask you to keep the volume down, because you’ve just entered the Library of Threats. While it may sound like inspiration for the next installment of National Treasure, you won’t find Nicolas Cage in this library (at least you shouldn’t). However, you will find Madeline Carmichael, MSTIC’s Threat Intel Librarian, whose movie-worthy title is just as impressive as it sounds. To be honest though, you might not find anyone in the library, as it bears more resemblance to Professor X’s Cerebro than it does your local hardcover sanctuary.  

 

In This Episode, You Will Learn:   

  • What the Pluton Security Processor is and how it was created 
  • The architecture of the Pluton Security Processor 
  • What challenges were faced while bringing the Pluton Security Processor to life 
  • The Root of Trust today vs. The Future with Pluton 
  • The naming systems for threat actors, from periodic elements to volcanoes 

 

Some Questions We Ask: 

  • What differentiates the Pluton Security Processor from previous methodologies? 
  • Why is the Pluton Processor better than what we have used in the past?   
  • What challenges lie ahead with the next steps around Pluton? 
  • What has changed since Pluton was in Xbox to where it is now? 
  • What tools and platforms does a Threat Intel Librarian utilize? 

 

Resources: 

Microsoft Pluton Announcement

Peter’s LinkedIn

Madeline’s LinkedIn 

Microsoft Security Blog

Nic’s LinkedIn

Natalia’s LinkedIn


Related:

Listen to: Afternoon Cyber Tea with Ann Johnson

Listen to: Security Unlocked: CISO Series with Bret Arsenault 

Discover and follow other Microsoft podcasts at microsoft.com/podcasts


Security Unlocked is produced by Microsoft and distributed as part of The CyberWire Network. 


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What A Day - If At First You Don’t Succeed, Trial, Trial Again

The second impeachment trial began yesterday, with Senators voting 56 to 44 to uphold the trial as constitutional and move forward. House managers presented video of the siege on the Capitol paired with Trump’s inflammatory speech to rally-goers beforehand, while Trump’s lawyers tried and failed to frame Trump’s impeachment after leaving office as a “slippery slope.”

A team from the World Health Organization has been in China investigating the origins of the coronavirus and they released preliminary findings yesterday. One prominent conspiracy theory they ruled out was the idea that the virus emanated from a Chinese lab, and they also said the virus had been circulating in Wuhan before its discovery at a seafood market.

And in headlines: hate crimes committed against Asian-Americans in the US is skyrocketing, the CEO of Riot Games faces a lawsuit for gender discrimination and misconduct, and the world’s first 3D printed T-bone steak.

Show Links:

"WATCH: Rep. Raskin presents graphic video timeline of Jan. 6 attack on U.S. Capitol"

https://www.youtube.com/watch?v=otfPps9s8HM


For a transcript of this episode, please visit crooked.com/whataday

The Goods from the Woods - “The Corona Diaries #119” with Narado Moore & Nick Thomas

Comedian Rivers Langley is back in his hometown in Alabama for the rest of 2020 and a bit of 2021. Also, there's a global pandemic still happening. This podcast is him catching up with his funny friends; sometimes on the phone, sometimes socially-distanced outside. These are "The Corona Diaries" and this is Episode #119.  We've got TWO very special guests on this episode in our middle segment: Narado Moore and Nick Thomas!  Follow Narado on all forms of social media @Rod4Short. Follow Nick on Twitter @OneDumbBoy and all the rest of his stuff at https://linktr.ee/NickThomas034  Listen to Carter Glascock's new album 'The Crystal Pistol' now streaming on all platforms!  Music at the end is "The Hustler" by Beachwood Sparks!

The Daily Signal - Andy Ngo Details ‘Antifa’s Radical Plan to Destroy Democracy’

In June of 2019, journalist Andy Ngo was attacked and beaten by Antifa. Ngo, the author of the new book "Unmasked: Inside Antifa's Radical Plan to Destroy Democracy," joins "The Daily Signal Podcast" to discuss the book, the agenda behind Antifa, the five months of Antifa riots in Portland during the summer of 2020, his on-the-ground investigations in which he actually goes inside the “black bloc” with Antifa members, and much more.


We also cover these stories:

  • Former President Donald Trump’s second Senate impeachment trial began Tuesday with a debate on the constitutionality of the trial itself.
  • During her confirmation hearing Tuesday, Neera Tanden, President Joe Biden's choice to head up the Office of Management and Budget, apologized for attacks she has made on Twitter on Republicans.
  • COVID-19 is likely to have originated in animals, according to a World Health Organization team tasked with finding the origin of the pandemic’s outbreak. 



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Philosophers In Space - Listener Qs 19

Thank you all so much! None of this would be possible without you!   Editing by Luisa Lyons, check out her amazing podcast Filmed Live Musicals: http://www.filmedlivemusicals.com/   Support us at Patreon: https://www.patreon.com/0G   Follow us on Twitter: https://twitter.com/0gPhilosophy   Join our Facebook discussion group (make sure to answer the questions to join): https://www.facebook.com/groups/985828008244018/   Email us at: philosophersinspace@gmail.com   If you have time, please write us a review on iTunes. It really really helps. Please and thank you!   Sibling shows:   Serious Inquiries Only: https://seriouspod.com/   Opening Arguments: https://openargs.com/ Embrace the Void: https://voidpod.com/   Recent appearances:  Aaron was on You might Have a Point discussing progressive liberalism https://www.youmighthaveapoint.com/6   CONTENT PREVIEW: Listener Qs 20

This Machine Kills - 42. The Machinery of Stupidity

Cold open: excerpt from Snow Crash by Neal Stephenson: https://www.youtube.com/watch?t=6021&v=ZypJn0PgAHA Have you ever considered that the most important human right is property rights? Are your thoughts preoccupied with kissing the feet of capitalists? Do you dream of abolishing society and clearing the way for the market god to deliver us into salvation? If so, you might just be the one of the all time greatest failsons of our age: David Friedman – whose life is consumed by trying to live up to the legacy of his father, Milton. In a blockbuster reading series, we liquefied our brains with David Friedman’s handbook for anarcho-capitalism. In this episode we lay out the philosophical foundations for why it’s actually good for everybody to act like children who don’t want to share their toys. I’m sorry in advance. The book we discuss: The Machinery of Freedom: Guide to Radical Capitalism by David Friedman http://www.daviddfriedman.com/The_Machinery_of_Freedom_.pdf Subscribe to hear more analysis and commentary in our premium episodes every week! patreon.com/thismachinekills Hosted by Jathan Sadowski (twitter.com/jathansadowski) and Edward Ongweso Jr. (twitter.com/bigblackjacobin). Production / Music by Jereme Brown (twitter.com/braunestahl).

60 Songs That Explain the '90s - No Doubt—“Just a Girl”

Rob explores ska-punk sensation No Doubt’s feminist anthem “Just a Girl” by discussing the rise of third-wave ska and Gwen Stefani’s turn as a solo artist.

This episode was originally produced as a Music and Talk show available exclusively on Spotify. Find the full song on Spotify or wherever you get your music.

Host: Rob Harvilla

Guest: Puja Patel

Producers: Isaac Lee and Justin Sayles

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