Serious Inquiries Only - SIO459: Understanding CRISPR with Dr. Eric Jaffe

In this episode, Dr. Eric Jaffe walks us through the history of CRISPR, how it works, how it's being used currently, and how it could be applied in the future. How quickly will we be able to eradicate mosquitoes? I say let's just do it, but Dr. Jaffe has some concerns.

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Planet Money - Rate Expectations

The Federal Reserve raised interest rates to get inflation under control. One side effect is that taking out a mortgage to buy a home has gotten very expensive. That's especially a problem for some homeowners who managed to get a lower mortgage rate years ago. They have a sort of... champagne problem. Or, "golden handcuffs" as it's called.

These homeowners may find they are "locked in" to their current home. In order to move to a new home, they have to take out a new mortgage at a much higher rate. It is one of the many problems plaguing the housing market right now.

The Fed is expected to start cutting rates next week. Will the golden handcuff mess finally start to unlock? And what does it mean for people looking to buy their first home?

On today's episode: We go deep into the golden handcuff problem and why it matters for everyone (including non-homeowners). We have FOMO about a big economic symposium in Jackson Hole, Wyoming. And we contemplate how to pronounce one of the most important interest rates in the economy: The IORB.

This episode was hosted by Kenny Malone and Alexi Horowitz-Ghazi. It was produced by Sean Saldana. It was edited by Jess Jiang and fact-checked by Sierra Juarez. Engineering by Cena Loffredo. Alex Goldmark is Planet Money's executive producer.

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Reset with Sasha-Ann Simons - WBEZ’s Weekly News Recap: Sept. 13, 2024

Chicago Mayor Brandon Johnson announces a hiring freeze to close a massive budget shortfall. The corruption trial of a former AT&T executive linked to Mike Madigan begins. Chicago’s City Council prepares to issue as much as $15 million in payouts for police misconduct. Plus, a new flag for Illinois? Reset dives into these and other top local stories in our Weekly News Recap with City Cast Chicago executive producer Simone Alicea, Block Club Chicago reporter Quinn Myers and WBEZ investigative reporter Dan Mihalopoulos. For a full archive of Reset interviews, head over to wbez.org/reset.

The Daily Signal - Trump Won’t Agree to Another Debate, Bomb Threat After ‘Eating the Pets’ Claim, Crime is Up Under Biden Administration | Sept. 13

TOP NEWS | On today’s Daily Signal Top News, we break down:


  • Former president Donald Trump says he will not debate Kamala Harris a second time. 
  • A bomb threat in Springfield, Ohio triggers the evacuation of city hall and local schools. 
  • The latest data out of the Crime Prevention Research Center has found that violent crime is up significantly in the past several years. 
  • The Daily Wire’s Matt Walsh is out with a new film. The movie is called “Am I Racist.”
  • “Reagan” movie review. 


Relevant Links

https://crimeresearch.org/2024/09/new-bureau-of-justice-statistics-crime-data-just-released-violent-crime-rape-robbery-and-aggravated-assault-soaring-under-biden/ 



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Motley Fool Money - Rich Signals from Berkshire

Normally people love reaching a milestone – but Berkshire Hathaway hitting $1T might’ve triggered a different kind of thinking for Warren Buffett and his lieutenants.


(00:21) Jason Moser and Matt Argersinger discuss:

- The signs execs at Berkshire Hathaway believe the market is rich – Ajit Jain reducing his Berkshire stake, and the company winding down its buyback activity.

- Brian Niccol’s vision for returning to Starbucks’ roots as a third place.

- Why the market was up on RH’s results, down on Adobe’s outlook, and still hoping a Kroger/Albertson’s deal will go through.


(19:11) This week was Apple’s annual product event. Dan Barbera from MacRumors gives the scoop on the latest releases, one way the latest iPhones could fuel Vision Pro adoption, and what to expect from Apple in 2025. 


(33:54) Jason and Matt break down two stocks on their radar: Top Golf Callaway and Oxford Industries.


Stocks discussed: BRK, SBUX, RH, ADBE, KR, AAPL, DNUT, OXM, MODG.


Host: Dylan Lewis

Guests: Jason Moser, Matt Argersinger, Dan Barbera

Engineers: Dan Boyd

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The Journal. - Fraudulent Online Returns Cost Retailers Billions

Scammers are exploiting retailers’ online return programs like never before, fueled by websites and messaging apps. WSJ’s Liz Young reports on the bind retailers now find themselves in, stuck between helping their customers and stopping the fraud.

 

Further Reading:

- Online Returns Fraud Finds a Home on Telegram, Costing Retailers Billions 

- Brick-Filled Boxes. Bogus Receipts. Retailers Battle Fraudulent Returns. 


Further Listening:

- How Cyber Thieves Are Disrupting U.S. Goods 

- The Slaves Sending You Scam Texts 


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CrowdScience - Is the car an apex predator?

An apex predator is a killer. Usually large and terrifying, they enjoy the privilege of life at the top of a food chain. Nothing will eat them, leaving them free to wreak carnage on more vulnerable creatures.

In biology, it’s a term normally reserved for animals like polar bears, tigers and wolves. But CrowdScience listener Eoin wonders whether there’s a non-animal candidate for apex predator: the car. After all, worldwide, more than 1.5 million humans die on the roads each year, while pollution from traffic kills millions more. And that’s just the impact on us. What are cars doing to all the other species on this planet?

Host Anand Jagatia hits the road to investigate. En route, we’ll be picking up some scientists to help answer the question. It turns out to be so much more than a question of roadkill: cars, and the infrastructure built to support them, are destroying animals in ways science is only now revealing.

How did the wildlife cross the road? We go verge-side to test four different approaches. And we hear how cars manage to kill, not just on the roadside, but, in the case of some salmon species, from many miles away. Gathering as much evidence as possible, we pass judgement on whether the car truly is an apex predator.

Contributors: Samantha Helle - Conservation Biologist and PhD student, University of Wisconsin–Madison Paul Donald – Senior Scientist, BirdLife International and Honorary Research Fellow, University of Cambridge Zhenyu Tian – Environmental Chemist and Assistant Professor, Northeastern University

Presenter: Anand Jagatia Producer: Marnie Chesterton Reporter: Camilla Mota Editor: Cathy Edwards Studio manager: Donald MacDonald and Giles Aspen Production co-ordinator: Ishmael Soriano

(Image: Illustration of a deer in front of a car - stock illustration Credit: JSCIEPRO/SCIENCE PHOTO LIBRARY via Getty Images)

CoinDesk Podcast Network - MARKETS DAILY: CoinDesk Markets Week in Review

CoinDesk Indices presents notable data insights from the week, followed by additional analysis from Marcin Kazmeerchak, co-founder & COO of Redstone Oracles.

To get the show every day, follow the podcast here.

The CoinDesk Market Index (CMI) functions as a benchmark for the performance of the digital asset market, delivering institutional quality information to digital asset investors. Subsets of the CoinDesk Market Index (CMI) are investable CoinDesk Crypto Sectors and the CoinDesk 20 Index, designed to measure the performance of top digital assets. Today’s takeaways are provided by Tracy Stephens, senior index manager at CoinDesk Indices with additional analysis from Marcin Kazmeerchak, co-founder & COO of Redstone Oracles.

For more on CoinDesk Indices, visit: coindeskmarkets.com.

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CoinDesk Podcast Network - UNCHAINED: Bitcoin Is Worth Over $1 Trillion. How Much Will Coinbase’s New cbBTC Grab?

Coinbase's new wrapped Bitcoin alternative, cbBTC, just launched. Will it challenge the dominance of WBTC in DeFi, or is it just another centralized solution? Coinbase’s VP of engineering, Will Robinson, breaks it all down.


On Thursday, Coinbase unveiled cbBTC, a tokenized version of Bitcoin on its Base layer 2 and Ethereum. This launch follows the recent BitGo controversy about the custody arrangement for Wrapped Bitcoin (WBTC) now involving Justin Sun, sparking concerns within the crypto community.

In this episode, Will Robinson, Coinbase’s VP of engineering, discusses the strategic importance of cbBTC, how it differs from other wrapped Bitcoin products, and what this means for the future of Bitcoin within DeFi ecosystems. 

Will Coinbase’s reputation as a "trusted custodian" be enough to make cbBTC the go-to choice for Bitcoin in DeFi, or will the industry remain skeptical?

  • Why Coinbase launched cbBTC and how it aims to bring Bitcoin into the world of DeFi
  • What happens behind the scenes when users mint cbBTC
  • What sets cbBTC apart from other wrapped Bitcoin options, according to Will
  • Whether Coinbase will expand cbBTC to other layer 2s and where users can already use it on major DeFi platforms
  • Will’s response to criticisms about the centralization of cbBTC
  • Why Coinbase's cbBTC launch was part of long-term plans, unrelated to the recent controversy around WBTC and Justin Sun
  • How Coinbase plans to make money from cbBTC, considering that WBTC has not been a big moneymaker for BitGo
  • Why Coinbase has the ability to freeze and blacklist cbBTC addresses
  • How Coinbase ensures that Bitcoin backing cbBTC remains the property of token holders and won’t be used as collateral or rehypothecated
  • Why Coinbase, a centralized entity, is launching cbBTC, a product for the decentralized, onchain world
  • Why Will doesn't want to predict how much demand there'll be for cbBTC

Visit our website for breaking news, analysis, op-eds, articles to learn about crypto, and much more: unchainedcrypto.com

Thank you to our sponsors!

Guest


Unchained Podcast is Produced by Laura Shin Media, LLC. Distributed by CoinDesk.

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Big Technology Podcast - OpenAI’s o1 Reasoning Model Debuts, $2,000 ChatGPT, AI News Anchors

Parmy Olson of Bloomberg joins for our weekly discussion of the latest tech news. She's also the author of the new book, Supremacy: AI, ChatGPT, and the Race that Will Change the World. We cover 1) OpenAI's release of its new o1 model, that can do reasoning, also know as Q* or Strawberry 2) o1's features and what makes it different 3) Businesses struggling to find o1 uses 4) Investor concerns over AI 5) A precursor to AI agents? 6) OpenAI raising at a $150 billion valuation now 7) Would people pay $2,000 per month for ChatGPT? 8) When will OpenAI have to return its investment? 9) Lessons about Sam Altman and Demis Hassabis from Parmy's book 10) AI news anchor avatars

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