Unexpected Elements - CORBEVAX – A vaccine for the world?

Now being produced in India CORBEVAX is grown in yeast in a similar way to several other widely available vaccines. The technology used to make it is far simpler and much more readily available than that used to produce mRNA vaccines. In theory, CORBEVAX could be produced cheaply in large quantities and go a long way to addressing the problems of Covid19 vaccine availability globally. It was developed by a team from Baylor College of Medicine in Texas including Maria Elena Bottazzi.

Antibiotic-resistant superbugs are thought to have emerged in repose to the use of antibiotics, however, the discovery of a superbug living on the skin of hedgehogs has challenged this view. The superbug is thought to have been living with hedgehogs long before antibiotics were discovered. Jesper and Anders Larsen at the Danish State Serum Institute in Copenhagen explain.

Modifying viruses, using them to infect or kill pest organisms is an attractive proposition. However, there are concerns over what might happen when they are released, particularly over their ability to mutate and evolve says Filippa Lentzos from Kings College Department of Global Health and Social Medicine in London.

And The Royal Botanical Gardens at Kew have released the names of over 200 new species of plants and fungi discovered last year. Mycologist Tuula Niskanen and botanist Martin Cheek tell us more.

Also... “I’m bored!” We can all relate to the uncomfortable - and at times unbearable - feeling of boredom. But what is it? Why does it happen? And could this frustrating, thumb-twiddling experience actually serve some evolutionary purpose? CrowdScience listener Brian started wondering this over a particularly uninspiring bowl of washing up, and it’s ended with Marnie Chesterton going on a blessedly un-boring tour through the science and psychology of tedium. She finds out why some people are more affected than others, why boredom is the key to discovery and innovation, and how we can all start improving our lives by embracing those mind-numbing moments.

(Image: Getty Images)

CrowdScience - Why do we get bored?

“I’m bored!” We can all relate to the uncomfortable - and at times unbearable - feeling of boredom. But what is it? Why does it happen? And could this frustrating, thumb-twiddling experience actually serve some evolutionary purpose? CrowdScience listener Brian started wondering this over a particularly uninspiring bowl of washing up, and it’s ended with Marnie Chesterton going on a blessedly un-boring tour through the science and psychology of tedium. She finds out why some people are more affected than others, why boredom is the key to discovery and innovation, and how we can all start improving our lives by embracing those mind-numbing moments.

Featuring: Prof James Danckert (University of Waterloo, Canada), Dr Elizabeth Weybright (Washington State University), Dr Christian Chan (Hong Kong University) and Annie Runkel (University of Dundee).

Presented by Marnie Chesterton Produced by Samara Linton

Image: Young Asian girl feeling lonely and bored at home. Screen addiction withdrawal symptoms (Credit: Oscar Wong, Getty Images)

Science In Action - Corbevax – A vaccine for the world?

Corbevax, which is being produced in India, is grown in yeast in a similar way to several other widely available vaccines. The technology used to make it is far simpler and much more readily available than that used to produce mRNA vaccines. In theory, Corbevax could be produced cheaply in large quantities to improve Covid-19 vaccine availability around the world. It was developed by a team from Baylor College of Medicine in Texas, including Maria Elena Bottazzi.

Antibiotic-resistant superbugs are thought to have emerged in response to the use of antibiotics. The discovery of a superbug living on the skin of hedgehogs has challenged this view. The superbug is thought to have been living with hedgehogs long before antibiotics were discovered. Jesper and Anders Larsen at the Danish State Serum Institute in Copenhagen explain.

Modifying viruses, using them to infect or kill pest organisms is an attractive proposition. However, there are concerns about what might happen when they are released, particularly over their ability to mutate and evolve, says Filippa Lentzos from Kings College Department of Global Health and Social Medicine in London.

And The Royal Botanical Gardens at Kew have released the names of over 200 new species of plants and fungi discovered last year. Mycologist Tuula Niskanen and botanist Martin Cheek tell us more.

(Image: Getty Images)

Presenter: Roland Pease Producer: Julian Siddle

30 Animals That Made Us Smarter - Slug and surgical glue

S2 Ep 28. From goo to super glue! Slug slime may hold the key to mending wounds without stitches or staples. Scientists have developed new adhesives based on the properties of slug slime, that are as sticky as any glue, stretchier than a rubber band and aren’t toxic to humans. This sticky substance could be used to repair a delicate organ like the heart or lung without using methods that could damage the organ. Get in touch: www.bbcworldservice.com/30animals #30Animals

World Book Club - Naoise Dolan: Exciting Times

The first of our season of celebrating The Exuberance of Youth in this the centenary year of the BBC, World Book Club talks to Irish writer Naoise Dolan about her dazzling novel Exciting Times. Psychologically astute and dryly funny, Exciting Times is a modern, intelligent dissection of youth, power and privilege set amongst the international circles of contemporary Hong Kong. Clever, young millennial Ava, an Irish graduate teaching English, is having an affair with rich cynical banker Julian. Then she meets Edith. Earnest, attentive and all the things Julian isn’t. A raw, intimate exploration of love and sexuality amongst millennials, Exciting Times charts the often transactional nature of relationships in our complicated modern world.

(Photo courtesy of Naoise Dolan.)

CrowdScience - How do you like your eggs in the morning?

Should you wash your eggs? Well believe it or not, there is quite an international debate about this question from CrowdScience listener Susan. In Canada, where Susan grew up, commercially sold eggs are washed before they reach stores, whereas in the UK where she is now living they are not. So what is best to avoid contamination?

It’s one of a number of egg-themed questions that CrowdScience tries to crack in this episode. One of our presenters, Marnie Chesterton, heads over to Susan’s home in London to cook some eggs and explore other egg cooking questions from our listeners, such as what is the science behind frying an egg without it sticking to the pan and why are some boiled eggs harder to shell than others?

Meanwhile this episode’s other presenter, Anand Jagatia, explores questions about eggs after they have hatched. He investigates a case of curious chicken behaviour sent in by listener Laurie, as well as working out how a cuckoo knows it’s a cuckoo when it’s been raised in another bird’s nest.

Presented by Marnie Chesterton and Anand Jagatia Produced by Jonathan Blackwell for BBC World Service

Featuring: Dr. Vincent Guyonnet, Dr. Valérie Lechevalier, Dr. Siobhan Abeyesinghe and Dr. Ros Gloag

(Photo credit: Getty Images)

Science In Action - 2021: The year of variants

In our first programme of the year, we gathered a group of scientific experts directly involved in analysing the structure and impact of the SARS- Cov-2 coronavirus. There were concerns over the emergence of two new variants, Alpha and Beta, especially whether these variants might spread more quickly, or outmanoeuvre the suite of new vaccines that were about to be rolled out. Now the same questions are being asked about the Omicron variant’s ability to spread and overcome our defences.

We’ve invited the same scientists back to give us their assessment of our journey with Covid-19 over the past year, and discuss their findings on Omicron.

The programme features: Ravi Gupta, Professor of Clinical Microbiology at the University of Cambridge Tulio de Oliveira, Professor of Bioinformatics, Stellenbosch University, South Africa Dr Allie Greaney from the Medical Scientist Training Program at the University of Washington School of Medicine Professor Jeremy Luban from the Broad Institute of MIT and Harvard

Presenter: Roland Pease Producer: Julian Siddle

Image: Local residents queue to receive a dose of the Covid-19 vaccine in Parkhurst, Johannesburg (Credit: Luca Sola/AFP via Getty Images)

30 Animals That Made Us Smarter - Dragonfly and sky spy

S2 Ep 27. The amazing agility of a dragonfly leads to the creation of a new spy drone. Their four wings can move independently of each other, enabling them to fly forwards, backwards, sideways, up and down and suddenly stop and hover like a helicopter. This caught the attention of engineers who wanted to develop a small drone that could be used by the military as a spying device. In the future, this sort of technology might send back pictures from areas where it’s too dangerous for humans to go. Get in touch: www.bbcworldservice.com/30animals #30Animals

Unexpected Elements - Omicron – mild or monster?

Studies from South Africa and the UK suggest Omicron may be a mild infection for the majority of people. Hospital admissions are down when compared with other variants. However, the virus is replicating at a much faster rate than earlier variants and is able to overcome vaccines to some extent. Cases studies so far have mainly been in young people. There is concern over what will now happen as Omicron spreads across Europe and the US where there are older unvaccinated populations. Anne von Gottberg from South Africa’s National Institute for Communicable Diseases tells us what early results from studies there show and discusses the implications.

Typhoon Rai in the Philippines led to the loss of many lives and even destroyed buildings designed to resist such extreme weather events. Could more have been done either to predict the ferocity of the typhoon or to prepare for its impact? Liz Stephens, Associate Professor in Climate Risks and Resilience from the University of Reading discusses these issues.

Beavers are making a comeback – in the Arctic. Their activity in engineering the landscape, building dams, and changing water courses is so widespread it can be picked out by satellites. However, this is not entirely welcome says Helen Wheeler Senior Lecturer in Zoology at Anglia Ruskin University. who has been working with local people concerned about the beavers impact on their livelihoods.

And the James Webb telescope is finally launching. Heidi Hammel, who has been involved in the project for over 20 years tells us what it’s all about.

Raindrops on roses and whiskers on kittens – CrowdScience has covered a lot this year. And what better way to see out 2021 than to look back at a few of our (and your!) favourite things? Great questions are right at the top of the team’s list – especially with the way that for every one we answer, five more appear in our inbox!

So for a festive treat, Marnie asks the crew to answer three of them. What's the sun's role in our sense of direction? Why are we so uncomfortable with other people’s sadness? And why does listening to the radio make us sleepy? (Or is it just too much eggnog…?) From our favourite listener advice on how to keep your Christmas lights untangled to why cold swimming could activate your Vagus nerve, tune in for new questions and more CrowdScience favourites to light up your holiday season!

Presented by Marnie Chesterton and many members the CrowdScience Team – Melanie Brown, Marijke Peters, Caroline Steel, Hannah Fisher, Samara Linton and Anand Jagatia. Produced by Sam Baker for BBC World Service.

Featuring:

• Haneul Jang, post-doctoral researcher, the Max Planck Institute for Evolutionary Anthropology • Juliet Rosenfeld, psychotherapist and author of The State of Disbelief: A Story of Death, Love and Forgetting • Mathias Basner, professor of psychiatry, University of Pennsylvania

(Image: Getty Images)