Unexpected Elements - Inserting human neurons into the brains of rats

Sergiu Pasca, Professor of Psychiatry at Stanford University has left the petri dish in the drawer and grown human neurons inside the brains of juvenile rats. Successful connectivity and brain function may allow for more rigorous testing and understanding of neurological conditions, that have until now remained difficult to localise and treat.

It’s been a few weeks since NASA’s DART mission smashed into an asteroid in an attempt to budge it off course, kickstarting Earth’s first planetary defence system. Scientists are starting to pour through the data to determine whether or not it worked. Dr Toney Minter, Head of Operations at Green Bank Observatory has been using Green Bank’s radio telescope to keep us updated and track the celestial system.

John Ryan, a Senior Research Specialist at Monterey Bay Aquarium Research Institute has spent the last three years studying the distinct vocal calls of blue whales. It’s part of a body of work that is unlocking the secretive existence of this endangered species, understanding how they react to the wind and search for food by navigating upwelling currents in the ocean.

Have you ever wondered what it would be like to live at the poles? Well, now you don’t have to imagine. Celas Marie-Sainte and Moreno Baricevic share their winterover experience, gathering data at the IceCube Neutrino Observatory in Antarctica. Hear what their work entails and ruminate on reflections of 6 months immersed in darkness.

And, One in every eight people live with a mental health disorder, so if that’s not you, it’s likely to be a close friend or family member. Despite there being a variety of known treatments, globally the majority of people suffering do not receive any medical support.

To see how the discussion around mental health is playing out across the African continent, CrowdScience visits Nairobi, Kenya. Presenter Marnie Chesterton is joined by a live audience and panel of experts - psychiatrist David Ndetei, psychotherapist Reson Sindiyo and mental health journalist Dannish Odongo - to get to the heart of what’s going on in our heads.

They discuss issues from taboo and superstition around mental health, to the treatment methods being used in Kenya that the rest of the world should know about.

(Image: Axial view of rat brain connectivity. Credit: Getty Images)

Presenter: Roland Pease Producer: Harry Lewis, Robbie Wojciechowski

CrowdScience - How is mental health being supported in Africa?

One in every eight people live with a mental health disorder, so if that’s not you, it’s likely to be a close friend or family member. Despite there being a variety of known treatments, globally the majority of people suffering do not receive any medical support.

To see how the discussion around mental health is playing out across the African continent, CrowdScience visits Nairobi, Kenya. Presenter Marnie Chesterton is joined by a live audience and panel of experts - psychiatrist David Ndetei, psychotherapist Reson Sindiyo and mental health journalist Dannish Odongo - to get to the heart of what’s going on in our heads.

They discuss issues from taboo and superstition around mental health, to the treatment methods being used in Kenya that the rest of the world should know about.

Science In Action - Inserting human neurons into the brains of rats

Sergiu Pasca, Professor of Psychiatry at Stanford University has left the petri dish in the drawer and grown human neurons inside the brains of juvenile rats. Successful connectivity and brain function may allow for more rigorous testing and understanding of neurological conditions, that have until now remained difficult to localise and treat.

It’s been a few weeks since NASA’s DART mission smashed into an asteroid in an attempt to budge it off course, kickstarting Earth’s first planetary defence system. Scientists are starting to pour through the data to determine whether or not it worked. Dr Toney Minter, Head of Operations at Green Bank Observatory has been using Green Bank’s radio telescope to keep us updated and track the celestial system.

John Ryan, a Senior Research Specialist at Monterey Bay Aquarium Research Institute has spent the last three years studying the distinct vocal calls of blue whales. It’s part of a body of work that is unlocking the secretive existence of this endangered species, understanding how they react to the wind and search for food by navigating upwelling currents in the ocean.

Have you ever wondered what it would be like to live at the poles? Well, now you don’t have to imagine. Celas Marie-Sainte and Moreno Baricevic share their winterover experience, gathering data at the IceCube Neutrino Observatory in Antarctica. Hear what their work entails and ruminate on reflections of 6 months immersed in darkness.

(Image: Axial view of rat brain connectivity. Getty Images) Credit:

Presenter: Roland Pease Producer: Harry Lewis, Robbie Wojciechowski

Focus on Africa - Both sides in Ethiopia conflict accused of crimes on civilians

Atrocities continue in northern Ethiopia - both sides accused of crimes against civilians.

Also, the first known ebola death in Kampala during the current outbreak: We speak to an expert about what the authorities should be doing to control it.

And we hear from a young Focus on Africa listener - aged 12 - who's creating computer games.

Those stories and much more in this podcast presented by Hassan Arouni.

Unexpected Elements - Nobel Prize 2022: The science behind the winners

For the scientific community, the Nobel Prize announcements are an important part of the yearly science calendar. The award is one of the most widely celebrated and gives us a moment to reflect on some of the leading scientific work taking place around the world.

This year’s winners include Alain Aspect, John F. Clauser, and Anton Zeilinger for their work on quantum entanglement. Carolyn R. Bertozzi, Morten Meldal, and K. Barry Sharpless for their work on click chemistry. And Svante Pääbo for his work on sequencing Neanderthal DNA.

To understand the science behind the award winners better, we’ve invited a variety of speakers to help us understand their work better. Award winner, Carolyn R. Bertozzi, Professor of Chemistry at Stanford, explains the basics behind click chemistry, a practice that has helped us to study molecules and their interactions in living things without interfering with natural biological processes.

Mateja Hajdinjak, Postdoctoral Training Fellow at the Max Planck Institute for Evolutionary Biology, celebrated alongside her former PhD. tutor, Svante Paabo in Germany this week. We talk to her about his significance in the development of DNA sequencing in ancient humans.

And Professor Shohini Ghose of the Institute of Quantum Computing at Waterloo University in Canada joins us to explain the complicated world of quantum entanglement.

Also this week, we meet Jessica Thompson, Assistant Professor of Anthropology at Yale University, who’s been considering how new parents manage the tricky job of childcare while out on fieldwork. She’s behind a new survey encouraging fellow scientists to consider how to approach the challenge of parental duties differently in the future.

Human sexuality comes in many forms, from exclusively heterosexual to exclusively homosexual. But seeing as homosexuality creates apparent reproductive and evolutionary disadvantages, listener Ahmed from Oslo wants to know: why are some people gay?

CrowdScience presenter Caroline Steel examines what science can - and can't - tell us about the role of nature, nurture and evolution in human sexual attraction. She asks a geneticist what we know of the oft-debated 'gay gene', as well as looking into why homosexual men on average have more older brothers than heterosexual men.

Caroline looks into the role of nurture with a developmental psychologist to answer a question from a CrowdScience listener from Myanmar. He wonders if the distant relationship he has with his own father has impacted his own feelings of attraction.

She also learns about research into a group of people in Samoa who may shed light on the benefits of traditionally non-reproductive relationships for communities as a whole.

(Photo: A monument to Nobel Prize founder Alfred Nobel. Credit: Mario Tama/Getty Images)

CrowdScience - Why am I gay?

Human sexuality comes in many forms, from exclusively heterosexual to exclusively homosexual. But seeing as homosexuality creates apparent reproductive and evolutionary disadvantages, listener Ahmed from Oslo wants to know: why are some people gay?

CrowdScience presenter Caroline Steel examines what science can - and can't - tell us about the role of nature, nurture and evolution in human sexual attraction. She asks a geneticist what we know of the oft-debated 'gay gene', as well as looking into why homosexual men on average have more older brothers than heterosexual men.

Caroline looks into the role of nurture with a developmental psychologist to answer a question from a CrowdScience listener from Myanmar. He wonders if the distant relationship he has with his own father has impacted his own feelings of attraction.

She also learns about research into a group of people in Samoa who may shed light on the benefits of traditionally non-reproductive relationships for communities as a whole.

Presented by Caroline Steel Produced by Jonathan Blackwell for BBC World Service

Contributors: Dr. Kevin Mitchell - Associate Professor of Genetics and Neuroscience, Trinity College Dublin Dr. Malvina Skorska - Postdoctoral Fellow at the Centre for Addiction and Mental Health, Toronto Prof. Lisa Diamond - Professor of Psychology and Gender Studies, University of Utah Prof. Paul Vasey - Professor and Research Chair, Department of Psychology, University of Lethbridge Vaitulia Alatina Ioelu - Chief Executive Officer, Samoa Business Hub

(Photo credit: Ahmed Umar)

Focus on Africa - Global alert over cough syrups

The World Health Organisation issues a global alert warning that four cough syrups manufactured in India could be linked to the deaths of dozens of children in The Gambia. We hear from the director of Health Services.

Also, why does the insurgency in Northern Mozambique continue five years on?

Plus, the prestigious Makrere University is 100 years old.

More on those and other stories in this podcast with Paul Bakibinga.

Science In Action - Nobel Prize 2022: The science behind the winners

For the scientific community, the Nobel Prize announcements are an important part of the yearly science calendar. The award is one of the most widely celebrated and gives us a moment to reflect on some of the leading scientific work taking place around the world.

This year’s winners include Alain Aspect, John F. Clauser, and Anton Zeilinger for their work on quantum entanglement. Carolyn R. Bertozzi, Morten Meldal, and K. Barry Sharpless for their work on click chemistry. And Svante Pääbo for his work on sequencing Neanderthal DNA.

To understand the science behind the award winners better, we’ve invited a variety of speakers to help us understand their work better. Award winner, Carolyn R. Bertozzi, Professor of Chemistry at Stanford, explains the basics behind click chemistry, a practice that has helped us to study molecules and their interactions in living things without interfering with natural biological processes.

Mateja Hajdinjak, Postdoctoral Training Fellow at the Max Planck Institute for Evolutionary Biology, celebrated alongside her former PhD. tutor, Svante Paabo in Germany this week. We talk to her about his significance in the development of DNA sequencing in ancient humans.

And Professor Shohini Ghose of the Institute of Quantum Computing at Waterloo University in Canada joins us to explain the complicated world of quantum entanglement.

Also this week, we meet Jessica Thompson, Assistant Professor of Anthropology at Yale University, who’s been considering how new parents manage the tricky job of childcare while out on fieldwork. She’s behind a new survey encouraging fellow scientists to consider how to approach the challenge of parental duties differently in the future.

Presenter: Roland Pease Producer: Harry Lewis Assistant Producer: Robbie Wojciechowski

(Photo: A monument to Nobel Prize founder Alfred Nobel. Credit: Mario Tama/Getty Images)

Focus on Africa - President Museveni’s son’s tweets raise eyebrows

In today's podcast:

Ugandans' tongues are wagging after a day which saw the President's son first demoted and then promoted to full General after a series of bizarre tweets that threatened to cause a diplomatic rift with neighboring Kenya.

Also, a $100 million dollar cocaine haul has been seized in Liberia by the Drugs Enforcement Agency, and a number of arrests made after a tip-off from the Americans, and it seems to point to a global syndicate.

Plus, thirteen women who'd been abducted from between three weeks to six months are rescued from their captors in Zambia.

Those stories and more in this podcast with Bola Mosuro.