Science In Action - Covid and clean air

We wouldn’t drink dirty water so why do we put up with polluted air? Researchers are calling for a major rethink on our attitude to air quality. Professor Lidia Morawska, from the Queensland University of Technology, says attention to air quality during the Covid pandemic has shown how levels of airborne disease can be reduced.

Sam Wilson from the UK Medical Research Council, University of Glasgow Centre for Virus Research has been investigating genetic mechanisms associated with susceptibility to Covid infection. His team has identified a molecule that detects SARS-COV-2 when it starts to replicate in our cells. However, not all humans have this protective mechanism, which may help explain why some people become very ill with Covid and others have little if any symptoms.

Many Europeans lack this protective molecule, whereas the vast majority of Africans have it. The difference can be seen in cell cultures. However, the lack of diversity in the cells used in experiments worldwide can be a serious problem when looking at genetic differences as Samara Linton reports.

Nuclear material buried beneath the doomed Chernobyl nuclear power plant is becoming more active Neil Hyatt Professor of Nuclear Materials Chemistry at Sheffield University says it’s a small increase but needs to be monitored.

(Photo by Sean Gallup/Getty Images)

Presenter: Roland Pease Producer: Alex Mansfield

Unexpected Elements - Africa’s oldest burial

Analysis of the 78,0000-year-old fossil of a Kenyan boy reveals he was likely buried with care and attention, the body wrapped and laid to rest supported on a pillow. Maria Martinon-Torres, of the National Research Centre on Human Evolution in Burgos, Spain, and a team from Kenya and Germany used techniques from paleontology and forensic science to reveal his story from the fragile remains.

A promising malaria vaccine is to enter trials which could lead to it being used globally to vaccinate children. Merheen Datoo, Oxford University’s Jenner Institute, explains malaria vaccines have been in development for 100 years. Research from these helped covid vaccine development and the success of covid vaccines may now help to speed up the rollout of malaria vaccines.

Covid vaccines may also help to treat those who have symptoms of long covid – a range of immune system issues that develop sometimes months after the initial infection. Yale University immunologist Akiko Kawasaki is embarking on a research project to assess the impact. If you’d like to take part, have yet to be vaccinated, and live in Connecticut in the US, email covidrecovery@yale.edu.

And in India scientists are calling on the government to make all data on Covid more widely available. At present Indian bureaucracy means statistics on infection rates, variants and recovery are not distributed widely. Science journalist TV Padma says greater access to the data could help more scientists come together to work on solutions to India’s Covid crisis.

And, Have you taken classes to learn a new sport or musical instrument or a language? It’s hard work! Why is it that as children we effortlessly absorb new skills and we don’t as adults?

That’s what 50-something listener Gary Grief wondered about playing guitar. Do you need to play more frequently as an adult to attain the same level of expertise? Does the 10,000-hours theory still apply?

Presenter and budding tabla-player Anand Jagatia embarks on a musical journey to discover what neuroscience can tell us about muscle memory and learning. Do musicians and sportsmen share the same challenges? By understanding what’s happening in the brain, can we learn how to learn better?

With tabla-teacher Satvinder Sehmbey, neuroscientist Dr Jessica Grahn, viola-player Dr Molly Gebrian and sports scientist Prof Yannis Pitsiladis.

(Image: An artist’s interpretation of Mtoto’s burial Credit: Fernando Fueyo)

CrowdScience - Why is learning stuff harder as you get older?

Have you taken classes to learn a new sport or musical instrument or a language? It’s hard work! Why is it that as children we effortlessly absorb new skills and we don’t as adults? That’s what 50-something listener Gary Grief wondered about playing guitar. Do you need to play more frequently as an adult to attain the same level of expertise? Does the 10,000-hours theory still apply? Presenter and budding tabla-player Anand Jagatia embarks on a musical journey to discover what neuroscience can tell us about muscle memory and learning. Do musicians and sportsmen share the same challenges? By understanding what’s happening in the brain, can we learn how to learn better? With tabla-teacher Satvinder Sehmbey, neuroscientist Dr Jessica Grahn, viola-player Dr Molly Gebrian and sports scientist Prof Yannis Pitsiladis. Presented by Anand Jagatia Produced by Dom Byrne for the BBC World Service

[Image: Adult and Child learning Piano. Credit: Getty Images]

Science In Action - Africa’s oldest burial

Analysis of the 78,0000-year-old fossil of a Kenyan boy reveals he was likely buried with care and attention, the body wrapped and laid to rest supported on a pillow. Maria Martinon-Torres, of the National Research Centre on Human Evolution in Burgos, Spain, and a team from Kenya and Germany used techniques from paleontology and forensic science to reveal his story from the fragile remains.

A promising malaria vaccine is to enter trials which could lead to it being used globally to vaccinate children. Merheen Datoo, Oxford University’s Jenner Institute, explains malaria vaccines have been in development for 100 years. Research from these helped covid vaccine development and the success of covid vaccines may now help to speed up the rollout of malaria vaccines.

Covid vaccines may also help to treat those who have symptoms of long covid – a range of immune system issues that develop sometimes months after the initial infection. Yale University immunologist Akiko Kawasaki is embarking on a research project to assess the impact. If you’d like to take part, have yet to be vaccinated, and live in Connecticut in the US, email covidrecovery@yale.edu.

And in India scientists are calling on the government to make all data on Covid more widely available. At present Indian bureaucracy means statistics on infection rates, variants and recovery are not distributed widely. Science journalist TV Padma says greater access to the data could help more scientists come together to work on solutions to India’s Covid crisis.

(Image: An artist’s interpretation of Mtoto’s burial Credit: Fernando Fueyo)

Presenter: Roland Pease Producer: Julian Siddle

World Book Club - Louise Penny: Still Life

This month World Book Club talks to acclaimed Canadian writer Louise Penny about the very first in her astonishingly successful series of Inspector Gamache crime novels.

When a much-loved inhabitant of the village of Three Pines in the Eastern Townships of Quebec is found dead in the woods during Thanksgiving, the locals are certain that it was just a tragic hunting accident.

But Chief Inspector Armand Gamache from Montreal suspects foul play and won’t rest until he’s rootled out the darkness at the heart of this seemingly peaceable and bucolic community. His always courteous but also insistent sleuthing gradually brings to light the family secrets and long-held grudges seething under its apparently serene surface.

(Picture: Louise Penny. Photo credit: Jean-Francois Berube.)

CrowdScience - Why are seeds such different sizes?

When eating a blackberry one day, CrowdScience listener Charles got a tiny seed stuck in his teeth. That got him wondering: why are seeds the size they are? Why does a blackberry have dozens of tiny pips, while a peach has one huge stone right in the middle?

Plant seeds have been around for hundreds of millions of years, so they’ve had plenty of time to shapeshift into wildly different forms: from dust-like orchid seeds to giant coconuts. This evolution has been a long and intricate dance with wind, water and animals; we ask how different kinds of seeds might respond to today’s environmental threats and rapidly changing ecosystems.

And we go in search of the world’s biggest seed, the coco de mer: native to just two remote islands in the Indian Ocean and weighing up to 18kg, how did this seed evolve to be so much bigger than any other?

With Professor Angela Moles, Dr Si-Chong Chen, Marc Jean-Baptiste, Dr Frauke Fleischer-Dogley and Dr Wolfgang Stuppy.

Presented by Marnie Chesterton Produced by Cathy Edwards for the BBC World Service

[Photo: Different sized fruit seeds. Credit: Getty Images]

Science In Action - Melting glaciers, warming coffee and a Dragonfly on Titan

When Apollo 11 astronaut Michael Collins – who passed away this week – looked down on the earth from lunar orbit during those days in 1969, he saw more ice and a smaller liquid ocean than you would see today. Of the 200,000 glaciers outside of the polar and Greenland ice sheets, their melting in the last two decades accounts for about a fifth of the sea level rise we are also seeing. Thus according to a paper published this week in the journal nature by, amongst others Bob McNabb of Ulster University who describes to Roland how and why these numbers are more certain than others before. As fellow earth observation expert Anna Hogg adds, the work synthesises years of data from almost half a million images of glaciers taken from space, and provides our best handle yet on our accelerating loss of this finite and dwindling natural feature.

Researchers at Kew in the UK and in Sierra Leone have rediscovered a species of coffee plant once thought lost. As Marnie Chesterton reports, climate change threatens many coffee crops around the world as the most popular variety – arabica – needs cool high altitude conditions which are going to become more scarce. But after a long and arduous search, the researchers have discovered a more resilient variety that might not only save the morning brew for many, it may even prove agriculturally and even economically transformative for some African economies.

And whilst many of us watch the antics of NASA’s Martian helicopter, Ingenuity, as it whizzes across the distant plains of “Wright’s Field” aerodrome on Mars, some are watching with more trepidation than others. In 6 years’ time, Zibi Turtle, Principle Investigator of NASA’s Dragonfly mission, hopes to launch a much larger octocopter drone to Titan, moon of Saturn. As she describes to Roland, the challenges are huge, not least because dragonfly will carry all its instruments on board as it hops around, finding new landing sites autonomously. And communicating with Earth will take a whopping hour each way.

(Image: The lunar module, carrying Neil Armstrong and Buzz Aldrin, ascends back up to the command module with Michael Collins. It is often said that Michael Collins is the only human, living or dead, who is not in this photograph. Credit: Michael Collins / NASA)

Presenter: Roland Pease Producer: Alex Mansfield

CrowdScience - What can we learn from wastewater?

Most of us don’t like to dwell on our toilet habits, but this week Crowdscience has gone down the drain to discover what wastewater can tell us about our health.

It’s been more than a year since scientists across the globe started to track the spread of Covid-19, with help from home test results and hospital data. Marnie Chesterton investigates the latest tool in their arsenal: sewage. Listener Kevin has heard how human waste can be monitored to check for virus levels, and wants to know if it can also be used to stop the disease in its tracks?

Although the coronavirus has been discovered in people’s poo, so far there’s little indication it’s actually being spread through the water system. But by taking regular samples from different parts of cities, authorities are now able to accurately predict a local peak weeks before the population shows signs of sickness, then take immediate measures to alert them. In Detroit we hear how environmental engineer Professor Irene Xagoraraki used this method to detect a rare strain of Herpes which doctors didn’t even know was a potential problem.

Marnie also talks to Professor Nick Thomson from the Wellcome Sanger Institute, who sequenced the genome of the bacteria that causes cholera, to understand how it has crisscrossed the globe. He discovered that the pandemic currently devastating Yemen actually originated in Asia. It’s a discovery that has changed how the WHO is thinking about this killer disease and could have important implications for vaccination programmes. But our effluent can also pose environmental problems, and Professor Andrew Johnson from the UK’s Centre for Ecology and Hydrology explains there are now as many as 300,000 chemicals that could threaten natural habitats.

While authorities try to test each one individually, he’s concerned they may have different effects when they mix in wastewater, and current monitoring systems don’t take this into account. Not only that, but some of these substances contain silver nanoparticles, which Professor Juliane Filser tells us stick around in soil for ever, threatening organisms and bacteria at the base of the food chain.

Presented by Marnie Chesterton and Produced by Marijke Peters for the BBC World Service.

[Image: Sewage outlets. Credit: Getty Images]

Science In Action - Exponential increase in Indian covid cases

As Covid cases surge almost beyond belief in India, how much is to do with social distancing, and how much to do with the mutations to the original virus?

Ramanan Laxminarayan talks to Roland from Delhi about ways in which the huge second wave could and could not have been predicted and avoided. Suggestions of the latest variant to make the headlines, B1.617, have got virologists such as Ravindra Gupta working hard to identify the clinical significance of the latest combinations of mutations.

In the journal Science, Stephen Chanock of the US Cancer program reports work with colleagues in Ukraine looking at the long footprint of radiation dosing from the Chernobyl nuclear disaster, 35 years ago this week. In the first of two papers, they find a definite footprint of radiation damage accounting for the many sad cases of thyroid cancer in people alive in the region at the time. But in another study, they looked at whether any higher level of mutations could be detected in the germlines of children conceived subsequently to parents who had experienced radiation in the disaster. While the parents' own health is often affected, 35 years on, thus far their offspring show no widespread elevated levels of disease, as was commonly expected.

And in the week that the world witnessed a guilty verdict delivered in the trial for the murder of George Floyd in the US, David Curtis of the University of Utah and colleagues report in the journal PNAS a study that suggests the widespread media coverage of acts of racial violence, including deaths at the hands of police, leads to poorer mental health in Black Americans. As the BBC’s Samara Linton reports, the study involved google search data over five years up to 2017, and nearly 2.3 million survey respondents.

Image: NurPhoto/Getty Images

Presenter: Roland Pease Reporter: Samara Linton Producer: Alex Mansfield

CrowdScience - Why does grief leave me feeling this way?

Grief is universal. It is something almost all of us will go through at some point. And it is something that the people we love will experience when we die.

Grief can be all consuming, it can make everyday tasks like getting out of bed, feel impossible. Which makes listener Oliver from Australia wonder - what is the point? It doesn’t bring what we lost, back.

Why have we evolved to be so affected by loss? Be it the death of a loved one, the end of a relationship or the loss of a job. Does it serve any purpose? Or perhaps it is just the price we pay for being a social species with such strong connections.

Image: Families Mourn Victims of The Tamaulipas Massacre in Tuilelén, Guatemala Photo by Josue Decavele/Getty Images

Produced by Caroline Steel and presented by Marnie Chesterton for BBC World Service.