Science In Action - Covid-19 vaccines

There are more than 100 different Covid-19 vaccine trials currently going on. We look at which seem to be the most promising with Helen Branswell from Stat News.

And we examine a very old idea, using antibodies from one virus – in this case Sars, to counter another virus Sars-CoV-2 , which causes Covid-19. Davide Corti from Vir Biotechnology says a version of these antibodies offers potential for both vaccination and treatment.

Race and Covid-19, there seems to be a link between ethnicity and susceptibility to the virus which can’t be easily explained away by economic factors. That's the finding from a study of nearly six million people in the US conducted by epidemiologist Chris Rentsch from the London School of Hygiene and Tropical Medicine.

And social distancing in ancient times, how plagues and pandemics in the past seem to have been defeated using similar behavioural adaptations to those we are current employing. Archaeologist Shadreck Chikure has seen the evidence in sites across Africa.

(Image:Vaccine trials Credit: Getty Images)

Presenter: Roland Pease Producer: Julian Siddle

Unexpected Elements - Loosening lockdown

How is Covid -19 spread? Who is most at risk and what are the circumstances under which it is most likely to be transmitted? These questions need answers for the implementation of effective and safe strategies to end lockdown. We look at what research is showing.

And if you have to go back to work what’s the best way to protect yourself, how should we be using face coverings for example? There are lessons from research on fluid dynamics.

Also key is reducing the rate of infection, the R number, Italy relaxed lockdown a few weeks ago we look at early findings on the impact.

It’s clear more widespread and effective testing will be needed to reduce transmission, A new test which should be quicker has been developed using synthetic biology and gene editing techniques.

Also despite being a universal need, talking about our toilet use and the infrastructure that aids us remains somewhat taboo. Whilst sectors like telecommunications and computing have undergone rapid transformations over the past century, the flush toilet and wastewater system have mostly remained unchanged.

CrowdScience listeners Linda and Allison wonder if flush toilets – and the clean water used to wash waste away - make economic or environmental sense. So CrowdScience presenter Marnie Chesterton looks under the toilet lid, to probe (in a sanitary fashion) whether our sewerage systems and plumbed toilets are fit for purpose. In a future where population growth and climate change are likely to affect water demands, can we continue to use clean water to dispose of our waste and should the developing world be emulating this model?

Around 2 billion people don’t have access to proper toilets or latrines, risking serious health consequences. Marnie investigates how countries without comprehensive sewerage infrastructure deal with human waste and how science is providing novel ways to dispose of - and use – human waste. Marnie speaks to a Kenyan scientist using poo-eating fly larvae to process faeces and a North American scientist who is developing a smart-toilet she hopes will monitor our health through sampling our daily movements. Are we ready to break taboos to innovate our toilet habits?

(Image: Commuters wear masks whilst travelling on a London Underground train. Credit: Tolga Akmen/Getty Images)

CrowdScience - Does my toilet make sense?

Despite being a universal need, talking about our toilet use and the infrastructure that aids us remains somewhat taboo. Whilst sectors like telecommunications and computing have undergone rapid transformations over the past century, the flush toilet and wastewater system have mostly remained unchanged.

CrowdScience listeners Linda and Allison wonder if flush toilets – and the clean water used to wash waste away - make economic or environmental sense. So CrowdScience presenter Marnie Chesterton looks under the toilet lid, to probe (in a sanitary fashion) whether our sewerage systems and plumbed toilets are fit for purpose. In a future where population growth and climate change are likely to affect water demands, can we continue to use clean water to dispose of our waste and should the developing world be emulating this model?

Around 2 billion people don’t have access to proper toilets or latrines, risking serious health consequences. Marnie investigates how countries without comprehensive sewerage infrastructure deal with human waste and how science is providing novel ways to dispose of - and use – human waste. Marnie speaks to a Kenyan scientist using poo-eating fly larvae to process faeces and a North American scientist who is developing a smart-toilet she hopes will monitor our health through sampling our daily movements. Are we ready to break taboos to innovate our toilet habits?

Presenter: Marnie Chesterton Producer: Melanie Brown

(Image: Man looking at toilet. Credit: Getty Images)

Science In Action - Loosening lockdown

How is Covid -19 spread? Who is most at risk and what are the circumstances under which it is most likely to be transmitted? These questions need answers for the implementation of effective and safe strategies to end lockdown. We look at what research is showing.

And if you have to go back to work what’s the best way to protect yourself, how should we be using face coverings for example? There are lessons from research on fluid dynamics.

Also key is reducing the rate of infection, the R number, Italy relaxed lockdown a few weeks ago we look at early findings on the impact.

It’s clear more widespread and effective testing will be needed to reduce transmission, A new test which should be quicker has been developed using synthetic biology and gene editing techniques.

(Image: Commuters wear masks whilst travelling on a London Underground train. Credit: Tolga Akmen/Getty Images)

Presenter: Roland Pease Producer: Julian Siddle

Unexpected Elements - Covid -19 new hope from blood tests

Research from New York examining the blood of people who have recovered from Covid – 19 shows the majority have produced antibodies against the disease, The researchers hope to soon be able to establish whether this confers long term immunity as with more common viral infections.

And Research in Berlin and London has identified biomarkers, minute signs of the disease which may help clinicians identify who is likely to develop severe symptoms and what kind of treatment they might need.

Mutations have been much in the headlines, these are a natural processes of evolution and not just in viruses, but the term is misunderstood, two studies focusing on different aspects shed some light on what mutation in SARS-CoV-2 really means.

Also What is the smallest particle of matter? How does radiation affect our bodies? And, how is particle physics useful in our everyday lives?

We take on particle physics questions from listeners all over the world. Marnie Chesterton and Anand Jagatia get help from particle physicists from the Large Hadron Collider at CERN and medical physicist Heather Williams.

(Image: People wear face masks as they cross a street in Times Square in New York City. Credit: Kena Betancur/AFP via Getty Images)

CrowdScience - What is the smallest particle?

What is the smallest particle of matter? How does radiation affect our bodies? And, how is particle physics useful in our everyday lives?

CrowdScience takes on particle physics questions from listeners all over the world. Marnie Chesterton and Anand Jagatia get help from particle physicists from the Large Hadron Collider at CERN and medical physicist Heather Williams.

Presented by Marnie Chesterton and Anand Jagatia Produced by Cathy Edwards, Jen Whyntie and Louisa Field

(Photo: Particle collider, Credit: Getty IMages)