Author: Loïc Houssier, Eira May, Ben Matthews

Ryan welcomes Anil Dash, writer and former Stack Overflow board member, back to the show to discuss how AI is not a magical technology, but rather the normal next step in computing’s evolution. They explore the importance of democratizing access to technology, the unique challenges that LLMs’ non-determinism poses, and how developers can keep Stack Overflow’s ethos of community alive in a world of AI. 

Episode notes: 

Anil is a tech entrepreneur (former CEO at our sister company Fog Creek Software) and writer. You can find him at his blog anildash.com and on Linkedin. 

Check out the last time Anil was on the pod in 2020 to talk all things Glitch and Glimmer. 

Shoutout to user pgrad for winning a Lifejacket badge on their answer to Using type hint Any in Django - NameError: name 'Any' is not defined.

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Ryan sits down with Corey Quinn, Chief Cloud Economist at Duckbill, at AWS re:Invent to get Corey’s patented snarky take on all the happenings from the conference. They discuss whether the AI agent hype is supported by actual buyers, how startups are faring as AWS focuses on large enterprises, and how many of the new technologies coming out this year will actually be transformative. 

Episode notes:

This episode was recorded at AWS re:Invent 2025! Check out Ryan’s recap of events on our blog. 

Duckbill provides financial planning and analysis for enterprise infrastructure to help you understand, negotiate, and optimize your cloud spend.

Connect with Corey on Linkedin and subscribe to his newsletter Last Week in AWS.

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Ryan is joined by Stack Overflow’s CEO Prashanth Chandrasekar and Director of Data Science Michael Foree on the floor at re:Invent to discuss all they’ve seen and heard at the event, from the future of AI agents to the trust issues the enterprise has around AI and the impact of AI and robotics on the job market.

Episode Notes:

This episode was recorded at AWS re:Invent 2025! Check out Ryan’s recap of events from the floor on our blog. 

Connect with Prashanth on LinkedIn.

Connect with Michael on LinkedIn.

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Ryan talks with Wesley Yu, head of engineering at Metalab, about the evolution of interfaces in technology, the pressure that UI generated on the fly would put on your backend systems, and why AI is just the latest and fanciest in a long line of CRUD apps. 

Episode notes:

Metalab designs interfaces for top brands around the world, helping them design, build, and ship their products.

Connect with Wesley on Twitter and LinkedIn.

Congrats to Populist badge winner SiddAjmera, who won the badge for their answer to Angular FormControl check if required.

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Ryan is joined by Kayvon Beykpour, CEO and founder of Microscope, to dive into AI-powered code review’s potential for managing large codebases, the need for humans-in-the-loop for reviewing PRs so AI tools can efficiently and effectively debug, and how AI can increase visibility  through summarization at the abstract syntax tree level and high signal-to-noise ratio code reviews.

Episode notes:

Macroscope helps you understand your code through AI-powered code review, automated PR descriptions, and real-time status reports

Connect with Kayvon on Twitter and LinkedIn.

This week’s shoutout goes to user Jesper Grann Laursen for winning a Populist badge on their answer to Exclude Table during pg_restore. 

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Ryan is joined by Outshift by Cisco’s VP of Engineering Guillaume De Saint Marc to discuss the future of multi-agent architectures as microservices, the challenges and limitations of the infrastructure for these multi-agent systems, and the importance of communication protocols and interoperability in order to build decentralized and scalable architectures. 

Episode notes:

Outshift is Cisco’s tech incubator that pursues emerging technologies like agentic AI, quantum computing, and next-gen infrastructure. Learn more about multi-agent architecture at their open-source collective AGNTCY.

Connect with Guillaume on Linkedin. 

Today we’re shouting out a Socratic badge winner, Avraam Mavridis, who won the badge for asking well received questions on 100 separate days.

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Ryan welcomes Simone Kalmakis, VP of Engineering at Viam, to dive into how her team is bridging the gap between software and robotics, the importance of abstraction layers in making robotics more accessible, and the real-world applications of robotics from lobster traps to industrial sanding robots.

Episode notes:

Viam is a robotics platform that brings modern software development tools into hardware applications. 

Connect with Simone on Linkedin. 

This week’s shoutout goes to Lifejacket winner Sergey Kalinichenko for their answer to How does this K&R code for reading an int work?.

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Darryl Lyons, co-founder and Chief Rainmaker at Rainstick, joins the show to dive into advancements in AgTech and how Rainstick is using bioelectricity to enhance agricultural productivity. They discuss how Rainstick mimics natural thunderstorms to create electric fields and frequencies that promote plant growth, challenges and breakthroughs in their research, and their participation in the AWS Compute for Climate Fellowship.

Episode notes:

Rainstick uses electricity to mimic the natural effects of lightning to grow crops bigger, faster, and more sustainably. 

Want to learn more about the Compute for Climate program? Check our podcast with Lisbeth Kaufman, Head of Climate Tech at AWS.

Ryan wrote about how software is being applied to agriculture a few years ago. 

Connect with Darryl on LinkedIn.

Congrats to Lifeboat badge winner WestCoastProjects for their answer to Test accuracy is greater than train accuracy what to do?.

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Ryan is joined by Jared Quincy Davis, CEO and co-founder of Mithril, to explore the importance of efficient resource allocation and GPU utilization in AI, the myth and misconceptions of the GPU shortage, and how the economics of GPU will change with new scheduling and utilization strategies. 

Episode notes:

Mithril’s omnicloud platform aggregates and orchestrates multi-cloud GPUs, CPUs, and storage so you can access your infrastructure through a single platform.

Connect with Jared on Twitter and LinkedIn.

Shoutout to user Razzi Abuissa for winning a Populist badge on their answer to How to find last merge in git?.

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Ryan is joined by David Hsu, CEO and founder of Retool, to explore how AI is transforming the role of a software developer into a software architect, the increasing accessibility of coding for non-engineers, and the importance of placing guardrails and higher-level programming primitives on AI coding assistants.

Episode notes:

Retool is an enterprise AI AppGen platform for internal software development, allowing you to create apps, agents, and workflows with any LLM, datasource, or API.

David Hsu previously joined the podcast to complain about maintaining internal tools. 

Connect with David on Twitter.

Today’s shoutout is for user Waseem Wisa, who won a Populist badge on their answer to Sass compiler throws 'undefined mixin' error when mixins are kept in seperate folder.

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