Consider This from NPR - FDA reverses decades of guidance on hormone therapy for menopause

The FDA is removing the black box warning on estrogen therapy after two decades. Should it?



Women who want to use estrogen to treat menopause symptoms often face a difficult choice.

That’s because those hormone treatments contain a “black-box warning.”

The Food and Drug Administration uses black box warnings to indicate a medication has potentially life threatening side effects.

In the case of estrogen for menopause symptoms, an increased risk of endometrial cancer, cardiovascular disorders, dementia and breast cancer.

Well those warnings are going away.  

For sponsor-free episodes of Consider This, sign up for Consider This+ via Apple Podcasts or at plus.npr.org. Email us at considerthis@npr.org.

This episode was produced by Mia Venkat and Erika Ryan. It was edited by Courtney Dorning and Scott Hensley.

Our executive producer is Sami Yenigun.

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1A - ‘If You Can Keep It’: The Results Of The 2025 Election

In the first general election since the beginning of Donald Trump’s second term, Democrats won big. But they might also be set to kill a lot of that momentum.

Exit polls have found that in major races across the country — in states like Virginia, New Jersey, New York, and California — the economy and affordability were the biggest issues that drove voters to the polls.

An NPB News poll from October suggests that 63 percent of registered voters believe the Trump administration has fallen short when it comes to the economy.

As part of our weekly series on the state of democracy, If You Can Keep It, we dive into some of the biggest local races and what they tell us about the issues that matter most to you – and what Democrats and Republicans can take away from this year’s results. 

But first, we dive into a potential deal to end the longest government shutdown in U.S. history that has some critics claiming Senate Democrats are caving to President Trump.

Find more of our programs online. Listen to 1A sponsor-free by signing up for 1A+ atplus.npr.org/the1a.

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Up First from NPR - Senate Shutdown Breakthrough, SNAP Legal Battle, COP30 Climate Summit Starts

Senate Democrats break ranks to join Republicans in backing a deal to reopen the government after 41 days, a move that could finally end the longest shutdown in U.S. history. SNAP benefits remain tangled in court battles, as a late ruling orders the Trump administration to fully restore payments while states face threats of federal penalties. And world leaders gather in Brazil for a major climate conference, but the Trump administration says the U.S. won't be at the table.

Want more comprehensive analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Anna Yukhananov, Kevin Drew, Neela Banerjee, Mohamad ElBardicy and Martha Ann Overland.

It was produced by Ziad Buchh, Nia Dumas and Lindsay Totty

We get engineering support from Stacey Abbott. And our technical director is Carleigh Strange.

Join us again tomorrow

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The Indicator from Planet Money - How the French pensions débâcle is a warning to us all

France has one of the most generous pension systems in the world. But several governments there have collapsed over questions about how the government will fund it. All over the world, aging populations are forcing governments to rethink their assumptions. 

Today on the show, what France’s political fiascos teach all of us about the economics of an aging population, and what a retirement expert’s ideal retirement system might look like.

Mercer CFA Institute Global Pension Index 2025

Related episodes: 

What would it take to fix retirement? 

What does the next era of Social Security look like? 

When Retirement Advice Goes Viral 

For sponsor-free episodes of The Indicator from Planet Money, subscribe to Planet Money+ via Apple Podcasts or at plus.npr.org. Fact-checking by Sierra Juarez. Music by Drop Electric. Find us: TikTok, Instagram, Facebook, Newsletter.  

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NPR's Book of the Day - Philip Pullman’s new novel follows ‘The Golden Compass’ heroine into young adulthood

It’s been more than 30 years since Philip Pullman began the His Dark Materials series – and now, that story is coming to a close. Pullman’s latest book The Rose Field follows the series’ heroine Lyra Belacqua as she chases the same mystery she began unraveling as a child. In today’s episode, Pullman joins NPR’s Scott Detrow for a conversation that touches on organized religion, reimagining Lyra as an adult, and a central concept in the series – Dust.

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Short Wave - Do Birth Control Side Effects Make It Worth Skipping?

Recently, health influencers on Instagram and TikTok have been vocal about the side effects of hormonal birth control. Check out the most popular videos on the subject, and you’ll hear horror stories about sex drive and skin texture, depression and weight fluctuation. But doctors say that while some side effects are possible, the most extreme stories are often the rarest cases. And one of the most common side effects of not taking birth control … is unplanned pregnancy. 

Interested in more health science? Email us your question at shortwave@npr.org.

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Consider This from NPR - ‘Affordability,’ and the repercussions of the increasing global wealth gap

‘Affordability’ was the word that resonated across America during elections last week, reflecting voters’ demand for elected officials to address the rising cost of living. But the wealth gap in America and globally is increasing. Nobel-prize winning economist Professor Joseph Stiglitz talks about the repercussions for democracies worldwide.

For sponsor-free episodes of Consider This, sign up for Consider This+ via Apple Podcasts or at plus.npr.org. Email us at considerthis@npr.org.

This episode was produced by Jordan-Marie Smith, with engineering by Peter Ellena.

It was edited by Ahmad Damen. Our executive producer is Sami Yenigun.

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Up First from NPR - Carlson’s War: Part 1


What does it mean to live through war? And can someone who’s experienced war ever get over it? These are questions NPR’s Quil Lawrence has been asking himself for years. A decade ago, Lawrence did a story on David Carlson, a veteran who’d excelled at being a soldier but struggled at home with PTSD, drugs and finally incarceration. Could Carlson find a way out or would the trauma of war come to define his life?
Listen to Part 2 here.

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Up First from NPR - Carlson’s War: Part 2

Part 2: In part two of Carlson’s War, we find Dave Carlson locked up in prison while tormented by PTSD from his time serving in Iraq. Alone and in pain, Carlson reverts back to a combat mindset and finds himself in a dark place. From here, Carlson sets out on a mission to turn his life around. What can we learn from one veteran’s journey to recovery?

If you haven’t heard Part 1, listen here

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