Since the age of nine or ten, Katie Burns has had debilitating pain from endometriosis, a condition where tissue resembling the uterine lining grows outside the uterus. For years, Katie was in the dark about what was causing her pain. Even after a diagnosis at age 20 it was hard to find relief, or even answers about her condition. Her search for better care is part of what led her to a career studying the disease, which affects tens of millions of people worldwide. And in 2012, she discovered something new about its origins. Today, we talk to Katie and science reporter Meredith Wadman about that discovery, which points to a surprising culprit of endometriosis — the immune system.
But since President Donald Trump took office in January, the administration’s sweeping cuts to the federal workforce and government funding are upending the country’s research system.
Our reporter in Gaza brings us scenes from Gaza City as Israel attempts to occupy the population center. A hospital courtyard has become a graveyard.
And we hear one expert’s take on whether recent announcements of countries recognizing a Palestinian state will make a difference in the peace process.
A superhuman artificial intelligence so smart it can decide to get rid of slower-witted humans is a pretty terrifying concept.
What was once strictly the stuff of science fiction is now closer than ever to being a reality.
And if it does, some A-I researchers have gloomy predictions about humanity’s chances of survival.
While the A-I boom continues and companies across the country are heavily investing in the technology, some researchers are begging humanity to pump the brakes.
A deadly shooting at a Dallas ICE office leaves one detainee dead and highlights rising violence around immigration enforcement. Ukraine's president warns that Russia’s war is fueling a dangerous new arms race as President Trump signals support for Ukraine reclaiming its territory. And a White House memo orders agencies to prepare mass firings if the government shuts down, with health care premiums still at the center of the standoff.
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Today’s episode of Up First was edited by Alfredo Carbajal, Miguel Macias, Diane Webber, Mohamad ElBardicy and Alice Woelfle.
It was produced by Ziad Buchh, Nia Dumas and Lindsay Totty.
We get engineering support from Stacey Abbott. And our technical director is Carleigh Strange.
Ken Jaworowski is out with a new crime novel with a surprising tender side. What About the Bodies is set in a fictional town past its glory days with a shuttered steel plant, closed coal mines, and a community that everyone talks about leaving. In today’s episode, the New York Times editor and author speaks with NPR’s Ayesha Rascoe about the three characters who converge in his story, the failed novels that predated this project, and why Jaworowski says he’s a better editor than writer.
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So, what fallout is the Trump administration’s immigration crackdown having on ICE detention centers? What are the conditions in these centers like? And what legal options do detainees have?
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Ukrainian President Volodymyr Zelensky addresses the United Nations the day after President Trump reversed his position on the war with Russia, saying Ukraine could win back all the territory it has lost. Meanwhile, Russia’s ramped up attacks on Ukraine in recent weeks have included more and more Russian aircraft entering the airspace of NATO countries. NATO has warned future incursions will lead to a more muscular response. We get updates from reporters in New York and Brussels.
The federal government’s approach to public health has changed more in the last eight months than it has in decades.
Since President Trump returned to office, he and members of his administration have challenged the safety of the covid vaccine, the overall childhood vaccine schedule, and the causes of autism.
This has upended public health guidance that doctors and patients have relied on for years.
Jen Brull, the President of the American Academy of Family Physicians talks about how doctors and patients are navigating this moment.
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