1A - The News Roundup For September 26, 2025

A gunman opened fire at an ICE detention facility in Dallas leaving one person dead and two more injured. All three of the victims were detainees and no ICE agents were hurt. The shooter was found dead according to senior law enforcement officials.

Late night host Jimmy Kimmel returned to the air on ABC this week. He was suspended after he made comments concerning the death of conservative activist Charlie Kirk.

The deadline to pass the government funding bill is fast approaching. The Trump White House is threatening mass firings if the government does shuts down.

And, in global news, President Donald Trump addressed the United Nations General Assembly this week. In a nearly hour-long speech, he attacked the U.N., criticized the immigration policies of its member states, and called climate awareness the “greatest con job ever perpetrated on the world.”

Spanish and Italian frigates were sent to protect the Global Sumud Flotilla. The boats carrying aid were attacked by drones on Tuesday.

And in a meeting on the sidelines of the U.N. General Assembly, Donald Trump said Ukraine could win back all its territory taken by Russia with NATO assistance.

We cover the most important stories here and around the globe in the News Roundup.

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Up First from NPR - Comey Indictment, Hegseth Summons Military Leaders, Impending Shutdown

Former FBI Director James Comey is indicted on obstruction and false statement charges after President Trump pressured the Justice Department to pursue a case. Defense Secretary Pete Hegseth orders an unprecedented global meeting of top U.S. military commanders, raising questions about what changes are coming. And Democrats accuse the White House of “mafia-style blackmail” as the shutdown fight intensifies over health care funding and the threat of mass federal layoffs. 

Want more comprehensive analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Krishnadev Calamur, Andrew Sussman, Kelsey Snell, Mohamad ElBardicy and Alice Woelfle.

It was produced by Ziad Buchh, Nia Dumas and Lindsay Totty

We get engineering support from Stacey Abbott. And our technical director is Carleigh Strange.

And our Executive Producer is Jay Shaylor

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NPR's Book of the Day - ‘Peacemaker’ and ‘Tomorrow Is Yesterday’ are personal histories of diplomacy

Two new books dive into the details of diplomacy. First, in the 1960s U Thant became the first non-Western secretary-general of the United Nations. Now his grandson, historian Thant Myint-U, has written Peacemaker, a new biography of the diplomat. In today’s episode, Thant speaks with NPR’s Michele Keleman about his grandfather’s journey. Then, Hussein Agha and Robert Malley have been a part of negotiations to end the conflict between Israel and Palestine. In today’s episode, they speak with NPR’s Scott Simon about their book Tomorrow Is Yesterday, a history of that failed peace process.


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The Indicator from Planet Money - Argentina’s bailout, a new way to cool data centers, and a cold holiday hiring season

It’s Indicators of the Week! It is that show where we parse the most fascinating financial numbers in the news and bring them to you. 

On today's show: Argentina needs a bailout, Microsoft’s new way to cool data centers, and retail hiring is not looking like it’s in the holiday spirit.

Related episodes:  

A radical plan to fix Argentina's inflation

What $10 billion in data centers actually gets you

For sponsor-free episodes of The Indicator from Planet Money, subscribe to Planet Money+ via Apple Podcasts or at plus.npr.org. Fact-checking by Sierra Juarez. Music by Drop Electric. Find us: TikTok, Instagram, Facebook, Newsletter 

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Short Wave - A Surprising Cause Of Endometriosis Could Lead To Cure

Since the age of nine or ten, Katie Burns has had debilitating pain from endometriosis, a condition where tissue resembling the uterine lining grows outside the uterus. For years, Katie was in the dark about what was causing her pain. Even after a diagnosis at age 20 it was hard to find relief, or even answers about her condition. Her search for better care is part of what led her to a career studying the disease, which affects tens of millions of people worldwide. And in 2012, she discovered something new about its origins. Today, we talk to Katie and science reporter Meredith Wadman about that discovery, which points to a surprising culprit of endometriosis — the immune system.


Read Meredith’s full piece in Science Magazine HERE


Interested in more health science ? Email us your question at shortwave@npr.org.


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1A - The Future Of Cancer Research In The US

More than 50 years ago, President Richard Nixon declared war on cancer when he signed the National Cancer Act in 1971.

Since then, the United States has emerged as a juggernaut in cancer research, funded largely by the government.

But since President Donald Trump took office in January, the administration’s sweeping cuts to the federal workforce and government funding are upending the country’s research system.

So, how are these funding and staffing cuts affecting cancer research and treatment? And how could they impact our progress towards scientific breakthroughs?

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State of the World from NPR - What Life is Like in Gaza; Will Recognition of a Palestinian State Make a Difference?

Our reporter in Gaza brings us scenes from Gaza City as Israel attempts to occupy the population center. A hospital courtyard has become a graveyard.

And we hear one expert’s take on whether recent announcements of countries recognizing a Palestinian state will make a difference in the peace process.

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Consider This from NPR - They warned about AI before it was cool. They’re still worried

A superhuman artificial intelligence so smart it can decide to get rid of slower-witted humans is a pretty terrifying concept.

What was once strictly the stuff of science fiction is now closer than ever to being a reality.

And if it does, some A-I researchers have gloomy predictions about humanity’s chances of survival.


While the A-I boom continues and companies across the country are heavily investing in the technology, some researchers are begging humanity to pump the brakes.


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Up First from NPR - ICE Shooting In Texas, UNGA: Ukraine Warning, Government Shutdown Standoff

A deadly shooting at a Dallas ICE office leaves one detainee dead and highlights rising violence around immigration enforcement. Ukraine's president warns that Russia’s war is fueling a dangerous new arms race as President Trump signals support for Ukraine reclaiming its territory. And a White House memo orders agencies to prepare mass firings if the government shuts down, with health care premiums still at the center of the standoff.

Want more comprehensive analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter.

Today’s episode of Up First was edited by Alfredo Carbajal, Miguel Macias, Diane Webber, Mohamad ElBardicy and Alice Woelfle.

It was produced by Ziad Buchh, Nia Dumas and Lindsay Totty.

We get engineering support from Stacey Abbott. And our technical director is Carleigh Strange.

Join us again tomorrow

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