Short Wave - Why The Trip Complicates Psychedelic Research

Researchers are studying psychedelics as a possible treatment for conditions like depression, PTSD and substance use disorders. But they don't know exactly how these drugs work.

Getting the answer to this question is especially difficult when people often take psychedelics like LSD and psilocybin for the "trip."

This week on Short Wave, we're talking to researchers about how they're trying to untangle the effects of this "trip" from the ways psychedelics might change the human brain ... and why the answer could help direct the future of psychedelic research.

Catch the rest of this series on psychedelics and related drugs this week by following us on Spotify and Apple Podcasts.

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PBS News Hour - Science - Why the military is creating artificial reefs to protect U.S. shorelines

Artificial, human-made reefs have been deployed around the country to enhance and protect coastlines. The Department of Defense is working to deploy them in waters off its coastal military bases with its “Reefense” project. Ali Rogin speaks with Catherine Campbell, who manages the program, to learn more. PBS News is supported by - https://www.pbs.org/newshour/about/funders

PBS News Hour - Science - Scientists work to restore wild ocelot populations with fertility treatments

While ocelots are widespread in South and Central America, in the United States they are on the brink of extinction. They were once overhunted for their coats, and now they face shrinking habitats. Researchers hope that the key to restoring this species can be found in fertility treatments. John Yang reports for our series, “Saving Species.” PBS News is supported by - https://www.pbs.org/newshour/about/funders

PBS News Hour - Science - How 200-year-old whaling logs are helping scientists track climate change

What can centuries-old whaling ship logs tell us about today’s extreme weather? According to scientists, the answer is a lot. They’re using the information recorded by mariners going back hundreds of years to push the frontier of modern-day climate science. Special correspondent Pamela Watts with Rhode Island PBS reports. PBS News is supported by - https://www.pbs.org/newshour/about/funders

CrowdScience - How do you measure a mountain?

On the banks of the St Lawrence River in Quebec stands a 100-year-old lighthouse. While initially built to help boats navigate one of Canada’s most difficult waterways, the Point-de-Père site now also holds a different responsibility: it is a key reference for measuring sea levels around the entire North America continent.

But this is all set to change. With the development of new satellite technology, the tricky task of measuring sea levels is being updated - which could mean mountains around North America get brand new official heights.

In this episode we revisit a question from CrowdScience listener Beth, who wondered about the elevation signs she saw scattered along a mountainous road, indicating how high above sea level she was. As sea levels rise, will all the elevation signs need repainting? And how do you measure sea level, anyway?

The height of an enormous pile of rock like Ben Nevis, or Mount Everest feels unchangeable. But we measure them relative to the nearest patch of sea, which is where our story becomes complicated. Unlike water in a bath, sea level is not equal around the world. In fact, nothing on earth - not the sea, the shore or the mountains - is stable or constant, so the question of what you measure from and to becomes incredibly tricky. But that hasn’t stopped scientists risking life and fingers to use an ever-evolving array of technologies to find answers.

Join host Marnie Chesterton as she dives into the mechanics of the latest sea level technology, and how it could make a big difference to understanding our unpredictable world.

Presenter: Marnie Chesterton Producer: Julia Ravey and Marnie Chesterton Editor: Cathy Edwards Production Co-ordinator: Ishmael Soriano and Jana Holesworth Studio Manager: Emma Harth

(Image: Elevation Sign Post, Rocky Mountain National Park. Credit: Stephanie Beverungen via Getty Images.)

Unexpected Elements - Oh, Rats!

On World Rat Day, we’re getting ratty! We look at the biology behind the eternal struggle between rats and rat poison, and we hear about rat-on-rat warfare and other forms of pest control.

We don’t play games when it comes to rats, but we know someone who does. Dr Michael Brecht from the Humboldt University of Berlin tells us how he played hide-and-seek with lab rats and what that tells us about the behaviour of play.

On the topic of ‘rat’ behaviour, we are joined by Dr Zach Berry from the University of Southern California to talk about the psychology behind ratting people out in the workplace, testing the loyalty and morals of the Unexpected Elements team.

And speaking of rats in the workplace… we hear a first-hand report on whether African giant pouched rats might just be better staff members than humans when it comes to detecting tuberculosis at APOPO labs.

All that, plus many more Unexpected Elements.

Presenter: Anand Jagatia, with Tristan Ahtone and Christine Yohannes Producer: Imaan Moin, with Debbie Kilbride, Alice Lipscombe-Southwell, Noa Dowling, Harrison Lewis and Sophie Ormiston. Studio Manager: Cath McGhee

Short Wave - Could Running Change Your Brain?

Running an entire marathon takes a lot of energy. Neuroscientist Carlos Matute knows this: he's run 18 of them. He wondered how runners' bodies get the energy they need to make it to the finish line.

His new research in the journal Nature Metabolism may be the first step in answering the question – and suggests their brains might be (temporarily) depleting a fatty substance that coats nerve cells called myelin.

Have other questions about the brain? Let us know by emailing shortwave@npr.org!

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Science In Action - Earthquakes and the first breath of life on Earth

How Myanmar’s tragic earthquake left a 500km scar on the surface of the earth in just 90 seconds. Also, more hints of a link between shingles vaccines and reduced dementia, and how earth’s first oxygen breathers seem to have evolved way before there was enough oxygen to breath.

Judith Hubbard is a seismologist and earthquake analyst who has been gleaning what scientific information we can find on the tragic quake that struck Myanmar last week.

There seems to be some sort of link between the herpes virus that causes shingles and some people’s risk of Alzheimer’s dementia. At least, the latest paper appears to confirm so, according to an analysis published in Nature this week. Pascal Geldsetzer of Stanford University and colleagues have looked at data from public health records in NHS Wales in the UK, and have retrospectively performed a “natural experiment”, finding a clear suggestion that a vaccine against the virus that causes shingles seems to confer a lower likelihood of developing dementia over the subsequent seven years. Quite why this happens remains moot.

And a long time ago, and for a long time, life on earth was nought but bacteria. The atmosphere was also nearly devoid of oxygen. These ancient bacteria leave scant fossil records, whilst the rocks show a clear time – known as the Great Oxidation Event – when earth’s atmosphere transformed to something more like the oxygen rich air we breath now. A pervading chicken-and-egg question asks whether the atmosphere changed and life adapted, or did life somehow evolve and transform the atmosphere? A team publishing in Science this week have performed an innovative analysis of bacterial genomes that suggests that the ability to use oxygen in respiration evolved some 900 million years before the atmosphere transformed. The question still stands, but as the team explain, the new analysis provides at least a clear timeline for why we breath the way we do today.

Presenter: Roland Pease Producer: Alex Mansfield Production Coordinator: Josie Hardy

(Image: People ride a scooter past the rubble of damaged Buddhist pagoda in Mandalay on April 3, 2025. Credit: Sai Aung MAIN / AFP via Getty Images)

Short Wave - Tornado Alley: Home Of Extreme Winds

Each year, the United States has about 1,200 tornadoes. Many of them happen in tornado alley, a very broad swath of the U.S. that shifts seasonally. This area gets at least ten times more tornadoes than the rest of the world. Science writer Sushmita Pathak says that huge difference can be chalked up to one word: geography. But there's a slice of South America with similar geographical features that gets comparatively fewer tornadoes, so what gives? Sushmita wades into the research weeds with guest host Berly McCoy, one of Short Wave's producers.

Read Sushmita's full article on tornadoes that she wrote for the publication Eos.

Have other science weather stories you think we should cover on the show? Let us know by emailing shortwave@npr.org!

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Social Science Bites - Jens Ludwig on American Gun Violence

Let’s cut to the chase: “The overwhelming majority of murders in the United States involve guns,” says economist Jens Ludwig. “And in fact, most of the difference in overall murder rates between the United States and other countries are due to murders with guns.”

This may seem intuitively obvious to outside observers, but studying guns within the United States has long been a fraught endeavor, and the amount of research isn’t commensurate with the impact on U.S. society. That said, Ludwig has taken on exploring the roots of American gun violence, work that serves as grist for the Crime Lab he directs at the University of Chicago and for many of his books, including his latest, Unforgiving Places: The Unexpected Origins of American Gun Violence. What’s he’s found is that the folk wisdom around gun violence doesn’t rally hold up to the evidence.

In this Social Science Bites episode, he explains to interviewer David Edmonds how – using insights about ‘system one’ and system two’ thinking developed by Daniel Kahneman – cognition in individuals has more explanatory power than traditional variables like poverty, education and environment.

“I think system one plays an underappreciated role in all interpersonal violence, all of the issues, and this way of seeing what is driving violent behavior among people is equally true for knife violence in the UK and on and on,” Ludwig says. “So I think this is really a universal thing about people's behavior. This sort of frame on the problem helps make sense of a bunch of patterns in the data.”

Ludwig is the Edwin A. and Betty L. Bergman Distinguished Service Professor at the University of Chicago, Pritzker Director of the Crime Lab and codirector of the Education Lab at that campus, and codirector of the National Bureau of Economic Research’s working group on the economics of crime.

He and his labs are routinely recognized for their work. The Crime Lab in 2014, for example, received a MacArthur Award for Creative and Effective Institutions, while eight years earlier Ludwig himself was awarded the Association for Public Policy Analysis and Management’s David N. Kershaw Prize for Contributions to Public Policy by Age 40. Some of the books he’s co-authored or co-edited include 2000’s Gun Violence: The Real Costs, 2003’s Evaluating Gun Policy, and 2012’s Controlling Crime: Strategies and Tradeoffs.