Short Wave - Why A Good Scare Is Sometimes The Right Call
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How we sleep is a topic of endless fascination and for some can, ironically be quite exhausting. Modern life has allowed us to invade the night, and those pesky late night work emails, social media and TV all conspire to limit our sleep or simply prevent us from a truly restful night. But if we travel back in time, did our ancestors master sleep any better? No air-con or electric fan for them on hot humid nights, and only smoky fires to keep them warm on cold, snowy nights. What if we go way back into our pre-history, to our ancient human ancestors? No interruption for them from an unwanted work email, however perhaps a ravenous lion gave them more reason for those night time worries.
CrowdScience listener Tom asks our sleep deprived presenter Datshiane Navanayagam to investigate how our sleep has changed over history and pre-history. She talks to Professor Russell Foster, Head of the Sleep and Circadian Neuroscience Institute at the University of Oxford and Neanderthal expert Dr Rebecca Wragg Sykes about slumber habits in days of yore, and in doing so, she uncovers some top tips from our ancestors that may give us all a better nights rest.
Presented by Datshiane Navanayagam and Produced by Alexandra Feachem
(Woman sitting in bed and yawning. Credit: JGI/Jamie Grill/Getty Images)
Indian authorities have approved the world’s first DNA-based Covid vaccine for emergency use. Not all the data that has led to the opening of the phase 3 trials is yet publicly available, but as public health policy expert Chandrakant Lahariya explains to Roland, it could be a real help in India’s, and the world’s, fight to get things under control.
The origins of the Covid virus were investigated last winter by a WHO team sent to Wuhan – where the first cases were discovered – earlier this year. Their work has since become the subject of intense political scrutiny and some criticism. This week, members of the team including Marian Koopmans have written a rebuttal, setting out the original terms of the investigation and urging the continuation of the process, as she explains to Victoria Gill.
Most of the science written by people from or about the African continent is written in English. Many local African languages do not currently have a meaningful vocabulary for many of the scientific terms and concepts researchers use. This week a team of scientists, journalists, and translators are completing the launch of a project called Decolonise Science, which will take 180 nominated papers posted on the website AfricaArxiv, translate them into 6 African languages including isiZulu, Sothu, and Hausa, and then use Machine Learning methods to build resources for science communication and education in people’s home languages. Project partner Sibusiso Byela explains the thinking.
This week the UK’s Royal Society announced its annual awards. Kenya’s George Warimwe has taken the Africa Award for his work creating vaccines for a virus that creates disease in livestock and humans – Rift Valley Fever. His promising approach stems from years of working with adenovirus technology akin to the AstraZeneca covid virus. But as he explains, his One Health approach is to learn from the immune response in humans and apply it to animals, and vice-versa. The grant associated with the award should also help him and his team pick- up on research left-off before the coronavirus pandemic.
Presenter: Roland Pease Producer: Alex Mansfield
(Image: Getty Images)
If you’ve ever fallen over and grazed your skin, maybe you wished it were made of stronger stuff. The tough hide of a rhinoceros or the protective armour of a stag beetle would do a better job. It’s a thought that’s been bothering CrowdScience listener Paul, who points out that our skin also suffers from acne, eczema and hives; it dries out; it bruises. In fact, human hide is so vulnerable that we cover our feet in other animals’ skin and our bodies in clothes just to make life more comfortable. Is this really the pinnacle of evolution?
Marnie Chesterton makes the case for the largest, fastest-growing organ, hiding in plain site on our body. Tissue Engineer Professor Sheila MacNeil from Sheffield University explains how skin manages to be breathable yet waterproof; flexible yet stronger than steel; sensitive to touch but protective against pollution and damaging UV. Skin biologist Dr Christina Philippeos from King’s College London explains how our bodies make a scar. Professor Muzlifah Haniffa has developed an atlas of the human skin – a tool to help researchers unravel the mysteries of how different skin cells interact. This atlas should help treat skin diseases in the future. Over in Tanzania’s Regional Dermatology Training Centre in Moshi, Dr Daudi Mavura talks us through a rare but devastating skin disorder called Xeroderma Pigmentosum, or XP. For children with XP, sunlight is dangerous because a mutation in the skin’s DNA repair mechanism means that UV rays can cause lesions and tumours.
Our epidermis is already multifunctional but over at Ben May Department of Cancer Research at the University of Chicago, Professor Xaioyang Wu and colleagues are looking at how much more skin could do. Personalised skin grafts may provide living drug patches to help people manage their disease, addiction or even weight.
With thanks to Dr Lynne MacTavish from Mankwe Wildlife Reserve in South Africa for describing a rhino’s skin.
Produced and presented by Marnie Chesterton.
[Image: Young and Old, dry skin Credit: Eric A. Nelson/Getty Images]