For the past 70 years, schizophrenia treatments all targeted the same chemical: dopamine. While that works for some, it causes brutal side effects for others. An antipsychotic drug approved last month by the FDA changes that. It triggers muscarinic receptors instead of dopamine receptors. The drug is the result of a chance scientific finding ... from a study that wasn't even focused on schizophrenia. Host Emily Kwong and NPR pharmaceutical correspondent Sydney Lupkin dive into where the drug originated, how it works and what it might shift for people with schizophrenia.
Every American red wolf alive right now is descended from only 14 canids. In the 1970s, humans drove the red wolf to the brink of extinction. Because of that, red wolves today have low genetic diversity. But what if we could recover that diversity ... using "ghost genes"?
That's right, today's episode is a ghost story. Along the way, we get into gene dictionaries, the possibilities of poo and how a photo of a common Texas coyote started it all.
Have another animal you want us to dig into for a future episode? Email us at shortwave@npr.org!
Calling all foragers! The new board game Undergrove, co-designed by Elizabeth Hargrave and Mark Wootton, is all about the symbiotic relationships between trees and fungi. Players assume the role of mature Douglas fir trees and partner with mushrooms, which represent the mycorrhizal network.
P.S. If the name "Elizabeth Hargrave" sounds familiar — she also designed the bird-collecting game Wingspan.
Have another science-backed board game you'd like us to play? Email us at shortwave@npr.org!
While there is a myriad of deodorants, shower gels and perfumes helping us stay fresh and fragrant today, that hasn’t always been the case. How did humans stay clean in the past, or did they not care so much? And is there an evolutionary reason for human body odour in the first place?
These are questions that CrowdScience listener Sarah has pondered on trips in her camper van, when she wants to keep clean, but washing isn’t always convenient.
In search of answers, presenter Anand Jagatia delves into the sweaty details: where body odour comes from, why some people's armpits don't smell, and whether this heady stink serves any purpose. Could our natural odour really help to attract a partner, or is it just a smelly bacterial by-product?
Anand explores the intriguing mystery of human pheromones, and hears how for hundreds of years, Europeans were terrified of washing.
Contributors:
Dr Madalyn Nguyen, Dermatologist
Dr Kara Hoover, Biological Anthropologist, University of Alaska Fairbanks
Katherine Ashenburg, author, The Dirt on Clean: An Unsanitized History
Dr Tristram Wyatt, Department of Biology, University of Oxford
Presenter: Anand Jagatia
Producer: Sophie Eastaugh
Production co-ordinator: Ishmael Soriano
Editor: Cathy Edwards
Sound engineer: Emma Harth
Spoiler alert! At the end of the fourth season of Emily in Paris, the protagonist sets off to go to Rome. In response, the French President Emmanuel Macron has promised that “we will fight hard” to keep Emily in Paris in France. Why does he care so much? A recent study suggests that 38 per cent of all visitors to Paris name the show as one of the reasons for visiting. Inspired by this factoid, we started thinking about the ways in which TV can influence us.
We examine how Star Trek inspired mobile phones – and the outfit of one of our panelists. Plus, we find out more about the impact Dana Scully from The X Files had on a generation of girls. And what does psychology say about fandom?
But how can science influence the films? We speak to Dr Adam Rutherford, a geneticist, broadcaster, and, importantly, scientific advisor for movies. What does that last role involve? Which films get the science right? And is scientific accuracy important for a Hollywood blockbuster?
Also in the programme, we hear about the mysterious recent earthquakes in Ethiopia, and Unexpected Elements listeners with visual impairments get in touch to share the secrets of what they can see inside their heads. And finally, we take a look at the surprising connection between cricket and statistics.
Presenter: Marnie Chesterton with Andrada Fiscutean and Christine Yohannes
Producer: Florian Bohr with Alice Lipscombe-Southwell and Anna Charalambou
Sound engineer: Cath McGhee
In the humid rainforests of northern and eastern Madagascar reside seven newly described frog species. They often hang out near fast, flowing rivers. These treefrogs' high-pitched, "futuristic" sounds may help male frogs attract females over the sound of nearby rushing water. They also are what inspired their Star Trek-themed names.
Have another animal you want us to dig into for a future episode? Email us at shortwave@npr.org!
The “dewilding” effects of fish farming and mariculture are in the spotlight this week. Farmed fish can impact marine ecosystems in several ways, and surprisingly one of those is the effect it has on consumer perceptions of the impact of eating farmed fish, as researchers Becca Franks of NYU and Laurie Sellars at Yale suggest.
Meanwhile, Manu Prakesh and colleagues at Stanford University in the US have found a remarkable plankton that can traverse the depths of the oceans by ballooning to five times its size, giving clues as to how an important carbon sink actually works. And Monika Bright at the University of Vienna has found animals and tubeworms living in the very rock below volcanic hydrothermal vents. Life finds a way…
…But not always. 445 million years ago the second worst mass extinction event wiped out countless species of life on earth. But why? This week astronomer Chrysa Avdellidou of Leicester University and colleagues say they have found the origin for a famous meteor event that also happened around that time.
Presenter: Roland Pease
Producer: Alex Mansfield
Production co-ordinator: Andrew Rhys Lewis
(Image: Aerial view of seagulls following a fishing trawler. Credit: Felix Cesare via Getty Images)
NASA's Europa Clipper mission launched Monday, beginning its years-long journey to the distant icy moon it's named after. This mission is designed to tell scientists more about the structure, the interior and the habitability of Europa, one of the four large moons of Jupiter. Host Regina G. Barber talks with astrobiologist and friend of the show Mike Wong about why their mutual love for this fascinating moon and what it means for the search for life outside of Earth. Plus, they talk about other icy moons that may also have the trifecta of ingredients needed to sustain life: liquid water, specific elements and an energy source. Want to hear more space science? Let your voice be heard by emailing shortwave@npr.org!
In honor of our show turning 5 (!!) today... 5 Short Wave staffers answer 5(x2) questions from some of our 5-year-old listeners and explain the science ... like they're 5.
SPOILER ALERT: The questions are brilliant, delightful and span everything from how colors work to insects, the formation of Earth and space.
Want to know more about the science of the world? Email us at shortwave@npr.org — we might cover it on a future episode!
Host Regina G. Barber talks with Rosalyn LaPier about ethnobotany--what it is and how traditional plant knowledge is frequently misunderstood in the era of COVID and psychedelics. And, how it's relevant and important for reproductive health today. (encore)
Have a topic you want us to cover on a future episode? Email us at shortwave@npr.org!