Once a relatively obscure class of drugs used for people with diabetes, GLP-1s have now shown an impressive ability to treat obesity, which affects over 100 million Americans. Horizons moderator William Brangham explores the great promise of the drugs and the potential concerns surrounding them with Dr. Jody Dushay, Dr. Rekha B. Kumar, Dr. Anna Lembke and Dr. Ziyad Al-Aly. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy
Around 2,500 U.S. Marines are heading for the Middle East, along with a Navy amphibious warship. Their mission is not yet clear, but it signals a marked increase in U.S. forces in the region. The deployment comes as the Pentagon said more than 15,000 targets had been struck in Iran over nearly two weeks of relentless bombing against the regime. Stephanie Sy reports. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy
As the war with Iran continues to escalate, northern Israel is yet again on the conflict's front line and facing a barrage of missile and drone fire. Communities still recovering from the fighting that followed the Oct. 7 attacks now again face the constant danger and mental trauma that comes with war. Nick Schifrin has the story. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy
After the Supreme Court overturned many of President Trump’s tariffs, his administration implemented new import taxes through a different legal avenue. But those are only temporary. Next up in the White House's game plan to claw those tariffs back? Unfair trade practice probes into dozens of countries — including several U.S. allies. Also in this episode: SNAP recipients sue the USDA over restrictive policies, a federal agency considers regulating prediction markets like Kalshi and Polymarket, and e-retailers hawk counterfeit skincare products.
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European leaders have reacted with alarm to a US plan to ease some oil sanctions on Russia. The intention, in Washington, is to tackle surging energy costs caused by the war in the Middle East, in particular the blockage by Iran of tanker traffic in the Strait of Hormuz, through which roughly 20 per cent of the world's oil usually transits. With her country at war with Russia, a Ukrainian MP gives us her reaction to this development.
Also on the programme: a look at the current state of Iran’s military capabilities as war continues to rage; how spider’s silk could be used to treat nerve damage in humans; and the bid to restore the resting place of saxophone inventor Adolphe Sax.
(Photo: General view of the Arcelor Mittal plant in Fos-sur-Mer, Southern France, 12th March 2026. Credit: Guillaume Horcajuelo/EPA/Shutterstock)
Today on The Gist, historic double Oscar-nominated director Geeta Gandbhir joins the show to discuss her Netflix documentary feature, The Perfect Neighbor. She breaks down the tragic murder of AJ Owens by her neighbor Susan Lorincz, explaining how Florida's "Stand Your Ground" laws, racial bias, and easy access to firearms enabled a deadly escalation. Gandbhir also explores the ethical complexities of using raw police body cam and Ring doorbell footage to document the community's grief without re-traumatizing the victim's family. Plus, why Defense Secretary Pete Hegseth is acting like a media critic instead of fighting an actual war. And in the Spiel, Donald Trump's repeated attempts to unlawfully install loyalist U.S. Attorneys keep getting smacked down by federal judges—proving the Constitution's guardrails are made of steel, not hanging by a thread.
Produced by Corey Wara
Video and Social Media by Geoff Craig
Do you have questions or comments, or just want to say hello? Email us at thegist@mikepesca.com
Experts say foreign conflict and online radicalization are accelerating threats of terrorism. Can anything slow it down?
Even before the war in Iran, the terrorism threat in the U.S. has been evolving. So how do the attacks of the past week fit into that picture? Host Scott Detrow speaks with Domestic Extremism Correspondent Odette Yousef, who is tracking all of this closely.
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This episode was produced by Connor Donevan and Marc Rivers, with audio engineering by Ted Mebane. It was edited by Andrew Sussman, Courtney Dorning and John Ketchum. Our executive producer is Sami Yenigun.
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On today’s show, we’re preparing for the Oscars by checking in on the state of the film industry. Marketplace’s Amy Scott sits down with Wall Street Journal entertainment reporter Ben Fritz to discuss what slumping ticket sales means for the future of movies, why the Paramount-Warner Bros. merger has Hollywood workers worried, and what it would take for the industry to make a comeback. Plus, movie watchers weigh in: subtitles on or off?
Monorepos -- you've heard the talks, you've read the blog posts, maybe you've seen a few tantalizing glimpses into how Google or Meta organize their massive codebases. But it's often in the abstract and behind closed doors. What if you could crack open a real, production monorepo, one with over a million lines of Python and over 100 of sub-packages, and actually see how it's built, step by step, using modern tools and standards? That's exactly what Apache Airflow gives us.
On this episode, I sit down with Jarek Potiuk and Amogh Desai, two of Airflow's top contributors, to go inside one of the largest open-source Python monorepos in the world and learn how they manage it with uv, pyproject.toml, and the latest packaging standards, so you can apply those same patterns to your own projects.
U.S. Attorney in Washington, D.C. says she'll appeal decision by federal judge to quash Federal Reserve subpoenas. Deaths of six service members when a refueling plane went down in Iraq was not result of Iran strike. Source tells CBS News brothers of driver who rammed into Michigan synagogue were members of Hezbollah.
