Tuberculosis – the world’s deadliest infectious disease – could be dormant in your system for years before you realize you have it. In the U.S., it’s relatively rare; provisional data shows that there were just over 10,000 cases in 2024. But in other parts of the world, especially lower-income countries, the disease is spreading much more actively. Worldwide, more than 10 million people are diagnosed with an active tuberculosis infection every year. And even though modern medicine has all the tools to cure it, over a million people around the world still die from the sickness annually.
Author John Green thinks that’s a problem. In his book Everything is Tuberculosis, he charts the spread of tuberculosis in the past to the lessons it has to teach us in the present.
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Today’s episode centers an important voice in the still-unfolding story of Jeffrey Epstein. Virginia Roberts Giuffre survived abuse at the hands of Epstein, Ghislaine Maxwell, and a number of powerful men. Giuffre died by suicide earlier this year. But before her death, she wrote a memoir called Nobody’s Girl. In today’s interview with NPR’s Leila Fadel, Giuffre’s collaborator on the project, Amy Wallace, and her brother, Sky Roberts, share what it was like for Giuffre to write about what she endured.
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Quarterly earnings reports are a long-standing requirement for public companies in the U.S. But the Trump administration wants to axe quarterly releases and just release them twice a year. And there is evidence to suggest this could be better in the long run for companies and investors. On today’s show, we look at the potential benefits and trade-offs of changing how often companies report their financial results.
Amazon has resolved the technical glitch that brought down thousands of apps and websites and disrupted online banking, social media websites and Amazon's retail operations. Also, an interim report says a defective cable caused the funicular crash that killed 16 people in the Portuguese capital, Lisbon; part of the White House is being demolished to make way for President Trump's new ballroom; and the ghostwriter of Virginia Giuffre's memoir speaks to the BBC as Prince Andrew comes under further pressure about his connections with the sex offender Jeffrey Epstein.
Ryan welcomes John Dickerson, CEO of Mozilla.ai, to talk about the evolving landscape of AI agents, the role of open source in keeping the tech ecosystem healthy, the challenges OS communities have faced with the rise of AI, and the implications of data privacy and user choice in the age of multi-agent AI systems.
Episode notes:
Mozilla.ai is building the agent platform that helps organizations safely automate real work with AI agents.
Connect with John on Linkedin or email him at john@mozilla.ai.
Secret Base’s sports-data auteur Jon Bois is back to preview a new series: a history and analysis of mound charges in baseball, coming this November. We talk a little bit about recent sports news including Dana White’s new boxing league, Shohei Ohtani’s generational run, and the Seattle Mariners (RIP). We then do a deep dive on former Reform Party member Curtis Sliwa, his statements about parades, Hasids, and cats, and his eating competition scandals. Finally, a quick check-in on Jordan Peterson’s recent health woes.
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Amanda Holmes reads Louise Glück’s “Brennende Liebe.” Have a suggestion for a poem by a (dead) writer? Email us: podcast@theamericanscholar.org. If we select your entry, you’ll win a copy of a poetry collection edited by David Lehman.
This episode was produced by Stephanie Bastek and features the song “Canvasback” by Chad Crouch.
In this episode, Dana El Kurd examines what we know about the new 20 point peace plan for the Israeli-Palestinian conflict, presented by President Trump. This plan helped facilitate a ceasefire in Gaza in the short term, but has dangerous limitations that will impact its success in the long term. This episode outlines the issues with this plan, with comparisons to other conflict resolution mechanisms around the world.