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Talk Python To Me - #519: Data Science Cloud Lessons at Scale

Today on Talk Python: What really happens when your data work outgrows your laptop. Matthew Rocklin, creator of Dask and cofounder of Coiled, and Nat Tabris a staff software engineer at Coiled join me to unpack the messy truth of cloud-scale Python. During the episode we actually spin up a 1,000 core cluster from a notebook, twice! We also discuss picking between pandas and Polars, when GPUs help, and how to avoid surprise bills. Real lessons, real tradeoffs, shared by people who have built this stuff. Stick around.

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Links from the show

Matthew Rocklin: @mrocklin
Nat Tabris: tabris.us

Dask: dask.org
Coiled: coiled.io
Watch this episode on YouTube: youtube.com
Episode #519 deep-dive: talkpython.fm/519
Episode transcripts: talkpython.fm
Developer Rap Theme Song: Served in a Flask: talkpython.fm/flasksong

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NBN Book of the Day - Charles R. Butcher and Ryan D. Griffiths, “Before Colonization: Non-Western States and Systems in the Nineteenth Century” (Columbia UP, 2025)

Today’s international system is made up of states: Territorial entities with defined borders, with exclusive control within those borders, diplomatic recognition by other states outside of them and usually (though not always) tied to some idea of the “nation.”

But how many states have existed throughout history, such as during the nineteenth century? Some early counts put the number at just a few dozen–a measure that international relations professors Charles R. Butcher and Ryan D. Griffiths thought was far too low, missing polities throughout the non-Western world. Together, they put together their own count of independent states in the nineteenth century, as published in their latest work Before Colonization: Non-Western States and Systems in the Nineteenth Century (Columbia UP, 2025).

Charles joins us today to talk about his work. He is a professor in the Department of Sociology and Political Science at the Norwegian University of Science and Technology. His research focuses on the legacies of historical states and state systems, democratization, and civil resistance.

You can find more reviews, excerpts, interviews, and essays at The Asian Review of Books, including its review of Before Colonization. Follow on Twitter at @BookReviewsAsia.

Nicholas Gordon is an editor for a global magazine, and a reviewer for the Asian Review of Books. He can be found on Twitter at @nickrigordon.

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What A Day - How NOT To Run The FBI

The investigation into the assassination of Charlie Kirk has raised a lot of questions – not just about the alleged shooter, but about the investigation itself. And especially about the person at the head of the bureau tasked with helping to find and capture suspects in acts of violence not just in the Kirk case, but across the country: FBI Director Kash Patel. His performance thus far has been, well, questionable. And he's tussling with Democrats who call him on it. To learn more about the FBI, Kash Patel, and how the Bureau is supposed to work, I spoke to Andrew McCabe, the FBI's former deputy director.

And in headlines, the Federal Reserve cut interest rates amid some less-than-stellar employment and inflation numbers, the former director of the Centers for Disease Control and Prevention testified to the Senate about her firing by Health and Human Services Secretary Robert F. Kennedy, Jr.,  and the U.K. rolls out the red carpet for President Trump.

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The NewsWorthy - Jimmy Kimmel Suspended, Interest Rate Cut & Iconic Toys  – Thursday, September 18, 2025

The news to know for Thursday, September 18, 2025!

We’ll tell you why late-night host Jimmy Kimmel has been pulled off the air indefinitely—and why it’s causing such a backlash.

Also, a new turning point for the Federal Reserve: the latest interest rate cut, and what the Fed says about the economy as a whole.

Plus: how the U.S. is changing the citizenship test, what the data says about the state of marriage in the U.S., and which toys could soon be recognized as Hall of Famers.

Those stories and even more news to know in about 10 minutes! 

 

Join us every Mon-Fri for more daily news roundups! 

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The Best One Yet - ☎️ “No you hang up!” — Landlines’ comeback. SharkNinja’s influencer army. The Fed’s D-Day. +Nike/Nobu Sushi Club.

Landline phones are making a comeback, led by the brand Tin Can… and it’s because of Millennial parents.

SharkNinja sells gadgets in 35 categories… and pays influencers $700M to promote them..

The Federal Reserve announced an interest rate cut… and declared independence.

Plus, Nike just launched a Sushi Club?... Welcome to the Nobu Sneaker era.


$SN $TMUS $SPY


Want more business storytelling from us? Check out the latest episode of our new weekly deepdive show: The untold origin story of… Sony’s Walkman 🎧


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The Indicator from Planet Money - Why “free” public education doesn’t always include school supplies

Back-to-school supplies are getting more expensive … so why are parents and teachers at public schools expected to foot the bill? Today on the show: An economist explains how the cost of school supplies fits into the larger history of public school funding, and what one school district is doing differently. 

Related episodes: 

A food fight over free school lunch 

Mailbag: Children Edition 


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NPR's Book of the Day - What Toni Morrison learned from revisiting five of her most-read novels

Arguably, no high school reading list is complete without one of Toni Morrison’s books. In today’s episode, we look back at a 2004 conversation between the author and NPR’s Renee Montagne, who visited Morrison to talk about a new paperback re-release of five of her novels. The interview focuses on Morrison’s perspective on hauntings, apparitions and ghosts, including the way Morrison’s late father helped her complete Song of Solomon.


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Tech Won't Save Us - Palantir is Thriving Under Trump w/ Caroline Haskins

Paris Marx is joined by Caroline Haskins to discuss what Palantir actually does and the growing influence it has within the US government and many large corporations.

Caroline Haskins is a staff writer at Wired.

Tech Won’t Save Us offers a critical perspective on tech, its worldview, and wider society with the goal of inspiring people to demand better tech and a better world. Support the show on Patreon.

The podcast is made in partnership with The Nation. Production is by Kyla Hewson.

Also mentioned in this episode:

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What Next | Daily News and Analysis - Trump’s Getting His Economy. Yikes.

Donald Trump has been calling for the Fed to cut rates to bolster the economy, and yesterday, they announced they would. The bad news is that’s because the economy is going to need a lot more bolstering.

Guest:  Justin Wolfers, economist and professor at the University of Michigan

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Podcast production by Elena Schwartz, Paige Osburn, Anna Phillips, Madeline Ducharme, and Rob Gunther.


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