A Chinese scientist, He Jiankui, made a shocking announcement to the world in 2018: He had secretly engineered the birth of the first gene-edited babies. The birth of the twins was seen as reckless and unethical by the scientific community. That’s because, among other things, the CRISPR gene-editing technique Jiankui used was so new. NPR science correspondent Rob Stein has been following the controversial world of gene-editing and human reproduction, including some companies’ recent quests to push gene-editing technology forward.
Read more of Rob Stein’s reporting on the topic here.
After using a Trump-stand-in during his first administration, South Park has come back from hiatus as vulgar and confrontational as ever, with its aiming firmly fixed on MAGA. Contrary to government sources, the show’s enjoying a renewed cultural relevance in its 27th season.
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Podcast production by Ethan Oberman, Elena Schwartz, Paige Osburn, Anna Phillips, Madeline Ducharme, and Rob Gunther.
Author Rax King says her new book of essays Sloppy is unified by themes of “addiction and bad habits.” King has been sober from alcohol and cocaine for three years and in these essays, she openly shares her sobriety journey. In today’s episode, King speaks with NPR’s Juana Summers about why the author doesn’t see addiction as a shameful secret, King’s relationship with her dad, and learning to generate creativity without substances.
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We begin by reading the last will and testament of Anas al-Sharif, a 28-year-old journalist for Al-Jazeera that was among those slain in Gaza by Israel yesterday. We then resume our Epstein coverage, including a look at his Manhattan lair and celebrity dinner guests. Then, two pieces on venture capitalists driven insane by The Computer and a story by Pamela Paul on conservative women…with careers? Stick around until the end for another Stroke of Genius and a special announcement from Chris.
Pre-order Seth Harp’s book The Fort Bragg Cartel here: https://www.penguinrandomhouse.com/books/730414/the-fort-bragg-cartel-by-seth-harp/
And check out his book launch with TrueAnon at the Bell House this Wednesday: https://www.ticketmaster.com/an-evening-with-trueanon-and-seth-brooklyn-new-york-08-13-2025/event/300062F5CD8E3E2D
How do we define liberty? Hayek saw it as the absence of most (but not all) coercion, but that depends upon how one defines “coercion.” Murray Rothbard believed that Hayek was too willing to accept forms of coercion that were anti-freedom.
A radical thought experiment transforms the lives of a new breed of philanthropists, as they follow the logic of altruism to extraordinary lengths. The most famous convert to the Effective Altruism movement, Sam Bankman-Fried, is either a humanitarian hero, a con artist at an astonishing scale, or most bafflingly, both.
For a full list of sources, see the show notes at timharford.com.
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Amanda Holmes reads Wislawa Szymborska’s “Hitler’s First Photograph,” translated from the Polish by Stanislaw Baranczak and Clare Cavanagh. Have a suggestion for a poem by a (dead) writer? Email us: podcast@theamericanscholar.org. If we select your entry, you’ll win a copy of a poetry collection edited by David Lehman.
This episode was produced by Stephanie Bastek and features the song “Canvasback” by Chad Crouch.