Serious Inquiries Only - SIO500: A New Study Suggests Brain Imaging Might Have Significant Flaws

Brain pics, or they didn't happen? There's a recent study that demonstrates that some brain region activity might interact differently with oxygen than previously assumed. This could upend significant neuroscience research spanning decades. Thankfully SIO has Dr. Jenessa Seymour to come in and break it all down for us!

We start with a primer on the science of neuroimaging tools and the images they produce. How in the WORLD can we get a picture of a brain while a person is still alive? What are the things we need to know when evaluating scholarly articles or popular media coverage about the brain that uses these brain "scans" in discussing their results? And what do we need to see next to support the findings of this study that could have incredible ramifications across our understanding of the brain?

Jenessa's brain sMRI

Are you an expert in something and want to be on the show? Apply here!

Please support the show on patreon! You get ad free episodes, early episodes, and other bonus content!

PBS News Hour - World - Trump signals Russia blocking path to peace as CIA rejects Putin’s drone attack claim

The CIA has assessed that Ukraine was not targeting a residence of Russian President Vladimir Putin in a recent drone attack, a claim that Putin told President Trump, and that Trump seemed to accept. Trump now suggests that he agrees with European leaders that it's Russia blocking the path to a peace agreement. Nick Schifrin discussed more with Angela Stent. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

PBS News Hour - World - Onboard an expedition to study a massive, melting glacier in Antarctica

Some call it the 'Doomsday Glacier,' a vast expanse of Antarctic ice roughly the size of Florida. As temperatures rise, the Thwaites Glacier is melting fast and threatens to raise global sea levels. That's why a team of nearly 40 researchers is embarking on a two-month journey to study it. Science correspondent Miles O'Brien is with the expedition and reports. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

PBS News Hour - World - Azerbaijan-Armenia peace plan hinges on narrow strip of land along Iran border

President Trump has claimed to have solved eight conflicts since he began his second term. One of those is between Azerbaijan and Armenia, rivals since the collapse of the USSR, whose leaders met with Trump in the Oval Office this summer. Special correspondent Simon Ostrovsky and producer Katia Patin travelled to the Armenian border with Iran to assess whether that agreement could lead to peace. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

Marketplace All-in-One - What’s next for the job market in 2026

Total jobless claims fell last week, which is the second-lowest reading in the last two years. Experts, though, say it’s likely a seasonal blip — especially since the labor market has been slowing all year. In this episode, what might be ahead in 2026. Plus: Los Angeles expands rent control, influencers change the consumer economy with “shopaganda,” and tribute bands get a moment in the spotlight.


Every story has an economic angle. Want some in your inbox? Subscribe to our daily or weekly newsletter.


Marketplace is more than a radio show. Check out our original reporting and financial literacy content at marketplace.org — and consider making an investment in our future.

PBS News Hour - Art Beat - Photojournalists reflect on capturing 2025’s most impactful images

We are taking our annual look back at some of the year's biggest images. We hear from four photojournalists who documented life on the frontlines in Ukraine, major changes in immigration enforcement in the U.S., the historic election of a new pope and more. It's part of our arts and culture series, CANVAS. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

PBS News Hour - Art Beat - Chloe Flower fuses classical and contemporary music in a style coined ‘popsical’

American pianist and composer Chloe Flower is on a mission to get young people into classical music. She's doing it by collaborating with rap, house and pop stars, and creating her own genre of music, a style she's coined "Popsical." Independent Television News correspondent Amelia Jenne reports. PBS News is supported by - https://www.pbs.org/newshour/about/funders. Hosted on Acast. See acast.com/privacy

The Gist - Chris Turner: Possession is 9/10 of the Word

Oxford-educated archaeology student turned freestyle sensation Chris Turner joins Mike Pesca to explain how his "British period" of deadpan one-liners evolved into the show-stopping rap flow that now defines his Comedy Cellar sets. Turner discusses the "evolutionary advantage" of not knowing the rules of hip hop as a ten-year-old in Manchester—a blissful ignorance that convinced him freestyling was just "making up a story"—and how he uses those same instincts to neutralize hecklers today. Along the way: a masterclass in the "tennis match" of flow state, the absurdity of 50 Cent's car-based fax machine, and a spontaneous freestyle that weaves together Jerry Springer, RFK Jr., and the "Antilles heel" of Hispaniola.

Produced by Corey Wara

Email us at ⁠⁠⁠⁠thegist@mikepesca.com⁠⁠⁠⁠

To advertise on the show, contact ⁠⁠⁠⁠ad-sales@libsyn.com⁠⁠⁠⁠ or visit ⁠⁠⁠⁠https://advertising.libsyn.com/TheGist⁠⁠⁠⁠

Subscribe to The Gist: ⁠⁠⁠⁠https://subscribe.mikepesca.com/⁠⁠⁠⁠

Subscribe to The Gist Youtube Page: ⁠⁠⁠⁠https://www.youtube.com/channel/UC4_bh0wHgk2YfpKf4rg40_g⁠⁠⁠⁠

Subscribe to The Gist Instagram Page: ⁠⁠⁠⁠GIST INSTAGRAM⁠⁠⁠⁠

Follow The Gist List at: ⁠⁠⁠⁠Pesca⁠⁠⁠⁠ ⁠⁠⁠⁠Profundities | Mike Pesca | Substack⁠⁠⁠⁠